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Don't blow it

Choose what's clinically proven to help reduce risk

3M™ Skin & Nasal Antiseptic is intended to help reduce bacteria on the skin that may cause surgical site infections.  It was demonstrated in a clinical study to help reduce the risk of surgical site infections by 81%*6 and helps you:

  • Better control compliance with a simple, one-time application
  • Reduce the risk of infection*3,6
  • Achieve cost-effective results3

*When part of a comprehensive preoperative protocol. 

 

 

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Why choose Skin and Nasal Antiseptic?

Your patients are counting on you - be sure you're doing everything you can to help prevent surgical site infections (SSIs). With a simple one-time application,8 you'll be able to reduce bacterial counts in the nares, including Staphylococcus aureus.1 Get it right the first time, every time with 3M™ Skin and Nasal Antiseptic.

Remove the variables

Achieve greater compliance by eliminating patient inconsistency with an easy one-time application at your facility.8

Reduce product cost-in-use

Lower estimated median total product cost-in-use than Nasal Antiseptic Kit 10% Povidone-Iodine or Nasal Sanitizer 62% Ethyl Alcohol.9

One-time application maintains effectiveness

Significantly reduce nasal bacterial counts, including S. aureus, by 99.5%, and maintain that reduction for at least 12 hours with a one-time application.*1

*As demonstrated through in vivo testing; mean values.

Extensively researched

Review the data. 3M™ Skin and Nasal Antiseptic has more than 10 published peer-reviewed and investigator-initiated studies and 20+ pieces of supporting evidence.

Choose our evidence-based Skin and Nasal Antiseptic as part of your nasal decolonization protocol.  It is intended to prepare the skin prior to surgery and help reduce bacteria that potentially can cause skin infections.

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Enhance patient safety in the ICU and the OR

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Make Skin and Nasal Antiseptic part of your nasal decolonization protocol

 

Confidence in surgery matters. Take control of your patients’ nasal decolonization with Skin and Nasal Antiseptic.

 

Designed to help address the rising concern of SSIs that can be caused by bacteria in the nares, this solution is a key element of patient preoperative skin preparation. By reducing the risk factors that contribute to SSIs, you can make a significant impact on patient outcomes. Using Skin and Nasal Antiseptic reduces bacteria in the nares, including Staphylococcus aureus, which is the leading cause of SSIs among adult and pediatric patients. By aligning with CDC, SHEA, IDSA, APIC and other leading organizations, you can help prevent SSIs.


 

We share your passion for infection prevention. Let us help you protect every patient, every time.

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Proven efficacy. Simple application

Make a real difference in your presurgical infection prevention protocol with Skin and Nasal Antiseptic (Povidone-Iodine Solution 5% w/w [0.5% available iodine] USP) Patient Preoperative Skin Preparation. Designed to prepare the skin prior to surgery and help reduce bacteria that potentially can cause skin infection. 

Chart image comparing Solventum Skin and Nasal Antiseptic to other competitor products. Provides information across a list of attributes.
When it comes to nasal antiseptics, formulation matters

 

Not all nasal decolonization solutions are created equally. 3M™ Skin and Nasal Antiseptic includes a unique polymer for longer efficacy.

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3M Skin and Nasal Antiseptic Application
  • Simple, one-time application 
  • Reduces bacteria in the nares including S. aureus by 99.5% in just 1 hour and maintains reduction for at least 12 hours*1​
  • Reduces bacteria on the abdomen by 99.7% and groin by 99.9% within 10 minutes and maintains for at least 6 hours*2

 

*As demonstrated through in vivo testing; mean values

Proven performance

Improves patient safety and protocol compliance without antibiotics.3

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In a randomized trial, 3M Skin and Nasal Antiseptic demonstrated a significant reduction of S. aureus SSIs (zero infections) compared to mupirocin, when used as part of a comprehensive protocol.3​

An iconographic representation of a sick patient paired with a representation of bacteria. Dark green and medium teal positive color palette.

Unique film-forming polymer increases persistence. 

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Solventum Peak Decolonization

Our decolonization assessment program analyzes current practices at your facility, enabling you to implement evidence-based protocols that reduce the risk of SSIs and enhance surgical outcomes.

Learn more about Peak
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Contact a Solventum representative

We're here to help! Our team of representatives can provide you with information and resources to help you. Submit the form below to speak with a Solventum representative to learn more about your options.

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References:

  1. 3M study 05-011100​
  2. 3M study 05-010945​
  3. Phillips M, Rosenburg A, Shopsin B, et al. Preventing surgical site infections;​ A randomized, open-label trial of nasal mupirocin ointment and nasal povidone-iodine​ solution. Infect Control Hosp Epidemiol.2014;35:826-832.​
  4. (Ex vivo porcine model): Anderson M, et al. 2015. Efficacy of Skin and Nasal Povidone-Iodine Preparation against mupirocin resistant MRSA and Staphylococcus aureus with the anterior nares, Antimicrob Agents Chemother. 2015 May;59(5):2765-73 pii: AAC.04624-14​
  5. Bebko SP, Green DM, Awad SS. Effect of a preoperative decontamination protocol​ on surgical site infections in patients undergoing elective orthopedic surgery with​ hardware implantation. JAMA Surg. Published online March 04, 2015.doi:10.1001/jamasurg.2014.3480.​
  6. Urias DS, Varghese M, Simunich T, Morrissey S, Dumire R. Preoperative decolonization​ to reduce infections in urgent lower extremity repairs. European Journal of Trauma and​ Emergency Surgery. 2018:17. doi:10.1007/s00068-017-0896-1.​
  7. Loftus RW, Dexter F, Goodheart MJ, et al. The Effect of Improving Basic Preventive​ Measures in the Perioperative Area on Staphylococcus aureus Transmission and​ Surgical Site Infections: A Randomized Clinical Trial. JAMA Netw Open.2020; 3(3):​e201934. doi:10.1001/jamanetworkopen.2020.1934.​
  8. Solventum internal data on file.​
  9. Premier Market Insights, Premier Inc. 2025. Data on file. Product cost-in-use per staffed bed. Based on ERP or transactional​ data from acute care facilities representing 25% of the entire U.S. acute care segment,​ data pulled 12/1/2024-12/31/2025.​
  10. Torres EG, Lindmair-Snell JM, Langan JW, Burnikel BG. Is preoperative nasal povidone-iodine as efficient and cost-effective as standard methicillin-resistant Staphylococcus aureus screening protocol in total joint arthroplasty? J Arthroplasty. 2016; 31:​215218.