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3M™ Zeta Plus™ EXT Series Filter Capsule with ZB Series Media

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3M™ Zeta Plus™ EXT Series Filter Capsule with ZB Series Media
3M Zeta Plus Depth Filter Noryl Production Capsules

About the product

The 3M™ Zeta Plus™ Encapsulated System Series with ZB Series Media are a single-use depth filtration system designed for the bioprocessing industry where upstream cell culture clarification or downstream impurity removal is required.

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Product name and IDs 3M ID Overall Width (Imperial) Overall Length (Imperial) Overall Length (Metric) Overall Width (Metric) Overall Diameter (Imperial) Overall Diameter (Metric) Filter Type Grade Application Filter Technology Industries Product Series Brand

3M ID

7100116976

Overall Width (Imperial)

17.8 inch

Overall Length (Imperial)

16 inch

Overall Length (Metric)

40.64 centimeter

Overall Width (Metric)

45.2 centimeter

Overall Diameter (Imperial)

-

Overall Diameter (Metric)

-

Filter Type

-

Grade

-

Application

Harvest and clarification

Filter Technology

-

Industries

Biopharmaceutical manufacturing

Product Series

ZB

Brand

Zeta Plus™

3M ID

7100101485

Overall Width (Imperial)

17.8 inch

Overall Length (Imperial)

16 inch

Overall Length (Metric)

40.64 centimeter

Overall Width (Metric)

45.2 centimeter

Overall Diameter (Imperial)

16 inch

Overall Diameter (Metric)

406.4 millimeter

Filter Type

Single-use Depth Filter

Grade

-

Application

Harvest and clarification

Filter Technology

-

Industries

Biopharmaceutical manufacturing

Product Series

Encapsulated

Brand

Zeta Plus™

3M ID

7100078370

Overall Width (Imperial)

-

Overall Length (Imperial)

-

Overall Length (Metric)

-

Overall Width (Metric)

-

Overall Diameter (Imperial)

-

Overall Diameter (Metric)

-

Filter Type

Depth

Grade

120ZB05A

Application

Harvest and clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

Product Series

ZB

Brand

Zeta Plus™

3M ID

7100069934

Overall Width (Imperial)

17.8 inch

Overall Length (Imperial)

2.24 inch

Overall Length (Metric)

5.7 centimeter

Overall Width (Metric)

45.2 centimeter

Overall Diameter (Imperial)

16 inch

Overall Diameter (Metric)

40.64 centimeter

Filter Type

Depth

Grade

120ZB10A

Application

Harvest and clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

Product Series

Encapsulated

Brand

Zeta Plus™

3M ID

7100049903

Overall Width (Imperial)

-

Overall Length (Imperial)

16 inch

Overall Length (Metric)

40.64 centimeter

Overall Width (Metric)

-

Overall Diameter (Imperial)

-

Overall Diameter (Metric)

-

Filter Type

Depth

Grade

60ZB05A

Application

Harvest and clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

Product Series

ZB

Brand

Zeta Plus™

3M ID

7100049901

Overall Width (Imperial)

-

Overall Length (Imperial)

16 inch

Overall Length (Metric)

40.64 centimeter

Overall Width (Metric)

-

Overall Diameter (Imperial)

-

Overall Diameter (Metric)

-

Filter Type

Depth

Grade

-

Application

Harvest and clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

Product Series

ZB

Brand

Zeta Plus™

3M ID

7100049900

Overall Width (Imperial)

17.8 inch

Overall Length (Imperial)

16 inch

Overall Length (Metric)

40.64 centimeter

Overall Width (Metric)

45.2 centimeter

Overall Diameter (Imperial)

-

Overall Diameter (Metric)

-

Filter Type

Depth

Grade

-

Application

Harvest and clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

Product Series

EXT

Brand

Zeta Plus™

3M ID

7100048216

Overall Width (Imperial)

17.8 inch

Overall Length (Imperial)

16 inch

Overall Length (Metric)

40.64 centimeter

Overall Width (Metric)

45.2 centimeter

Overall Diameter (Imperial)

16 inch

Overall Diameter (Metric)

40.64 centimeter

Filter Type

Single-use Depth Filter

Grade

-

Application

Harvest and clarification

Filter Technology

-

Industries

Biopharmaceutical manufacturing

Product Series

Encapsulated

Brand

Zeta Plus™

3M ID

7100035917

Overall Width (Imperial)

-

Overall Length (Imperial)

-

Overall Length (Metric)

-

Overall Width (Metric)

-

Overall Diameter (Imperial)

-

Overall Diameter (Metric)

-

Filter Type

-

Grade

-

Application

Harvest and clarification

Filter Technology

-

Industries

Biopharmaceutical manufacturing

Product Series

Encapsulated

Brand

Zeta Plus™

3M ID

7100035282

Overall Width (Imperial)

17.8 inch

Overall Length (Imperial)

7.99 inch

Overall Length (Metric)

20.3 centimeter

Overall Width (Metric)

45.2 centimeter

Overall Diameter (Imperial)

16 inch

Overall Diameter (Metric)

40.64 centimeter

Filter Type

Depth

Grade

120ZB08A

Application

Harvest and clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

Product Series

EXT

Brand

Zeta Plus™

3M ID

7100029898

Overall Width (Imperial)

17.8 inch

Overall Length (Imperial)

16 inch

Overall Length (Metric)

40.64 centimeter

Overall Width (Metric)

45.2 centimeter

Overall Diameter (Imperial)

16 inch

Overall Diameter (Metric)

40.64 centimeter

Filter Type

Depth

Grade

120ZB10A

Application

Harvest and clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

Product Series

EXT

Brand

Zeta Plus™

3M ID

7100026714

Overall Width (Imperial)

17.8 inch

Overall Length (Imperial)

16 inch

Overall Length (Metric)

40.64 centimeter

Overall Width (Metric)

45.2 centimeter

Overall Diameter (Imperial)

-

Overall Diameter (Metric)

-

Filter Type

Depth

Grade

90ZB08A

Application

Harvest and clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

Product Series

Encapsulated

Brand

Zeta Plus™

3M ID

7100021689

Overall Width (Imperial)

17.8 inch

Overall Length (Imperial)

7.99 inch

Overall Length (Metric)

20.3 centimeter

Overall Width (Metric)

45.2 centimeter

Overall Diameter (Imperial)

16 inch

Overall Diameter (Metric)

40.64 centimeter

Filter Type

Depth

Grade

60ZB05A

Application

Harvest and clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

Product Series

EXT

Brand

Zeta Plus™

3M ID

7010409939

Overall Width (Imperial)

17.8 inch

Overall Length (Imperial)

7.99 inch

Overall Length (Metric)

20.3 centimeter

Overall Width (Metric)

45.2 centimeter

Overall Diameter (Imperial)

16 inch

Overall Diameter (Metric)

40.64 centimeter

Filter Type

Depth

Grade

90ZB

Application

Harvest and clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

Product Series

Encapsulated

Brand

Zeta Plus™

3M ID

7010381458

Overall Width (Imperial)

-

Overall Length (Imperial)

16 inch

Overall Length (Metric)

40.64 centimeter

Overall Width (Metric)

-

Overall Diameter (Imperial)

-

Overall Diameter (Metric)

-

Filter Type

-

Grade

-

Application

Harvest and clarification

Filter Technology

-

Industries

Biopharmaceutical manufacturing

Product Series

ZB

Brand

Zeta Plus™

3M ID

7010381437

Overall Width (Imperial)

17.8 inch

Overall Length (Imperial)

7.99 inch

Overall Length (Metric)

20.3 centimeter

Overall Width (Metric)

45.2 centimeter

Overall Diameter (Imperial)

16 inch

Overall Diameter (Metric)

40.64 centimeter

Filter Type

Depth

Grade

60ZB

Application

Harvest and clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

Product Series

Encapsulated

Brand

Zeta Plus™

3M ID

7010381432

Overall Width (Imperial)

17.8 inch

Overall Length (Imperial)

2.24 inch

Overall Length (Metric)

5.7 centimeter

Overall Width (Metric)

45.2 centimeter

Overall Diameter (Imperial)

16 inch

Overall Diameter (Metric)

40.64 centimeter

Filter Type

Depth

Grade

90ZB

Application

Harvest and clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

Product Series

Encapsulated

Brand

Zeta Plus™

3M ID

7010381431

Overall Width (Imperial)

17.8 inch

Overall Length (Imperial)

2.24 inch

Overall Length (Metric)

5.7 centimeter

Overall Width (Metric)

45.2 centimeter

Overall Diameter (Imperial)

16 inch

Overall Diameter (Metric)

40.64 centimeter

Filter Type

Depth

Grade

60ZB

Application

Harvest and clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

Product Series

Encapsulated

Brand

Zeta Plus™

3M ID

7010339026

Overall Width (Imperial)

17.8 inch

Overall Length (Imperial)

7.99 inch

Overall Length (Metric)

20.3 centimeter

Overall Width (Metric)

45.2 centimeter

Overall Diameter (Imperial)

16 inch

Overall Diameter (Metric)

40.64 centimeter

Filter Type

Depth

Grade

120ZB

Application

Harvest and clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

Product Series

Encapsulated

Brand

Zeta Plus™

3M ID

7010339022

Overall Width (Imperial)

17.8 inch

Overall Length (Imperial)

2.24 inch

Overall Length (Metric)

5.7 centimeter

Overall Width (Metric)

45.2 centimeter

Overall Diameter (Imperial)

16 inch

Overall Diameter (Metric)

40.64 centimeter

Filter Type

Depth

Grade

120ZB

Application

Harvest and clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

Product Series

Encapsulated

Brand

Zeta Plus™

3M ID

7010301515

Overall Width (Imperial)

17.8 inch

Overall Length (Imperial)

7.99 inch

Overall Length (Metric)

20.3 centimeter

Overall Width (Metric)

45.2 centimeter

Overall Diameter (Imperial)

16 inch

Overall Diameter (Metric)

40.64 centimeter

Filter Type

Depth

Grade

30ZB

Application

Harvest and clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

Product Series

Encapsulated

Brand

Zeta Plus™

3M ID

7010301514

Overall Width (Imperial)

17.8 inch

Overall Length (Imperial)

2.24 inch

Overall Length (Metric)

5.7 centimeter

Overall Width (Metric)

45.2 centimeter

Overall Diameter (Imperial)

-

Overall Diameter (Metric)

-

Filter Type

Depth

Grade

30ZB

Application

Harvest and clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

Product Series

Encapsulated

Brand

Zeta Plus™

3M ID

7000144885

Overall Width (Imperial)

17.8 inch

Overall Length (Imperial)

16 inch

Overall Length (Metric)

40.64 centimeter

Overall Width (Metric)

45.2 centimeter

Overall Diameter (Imperial)

16 inch

Overall Diameter (Metric)

40.64 centimeter

Filter Type

Depth

Grade

90ZB08A

Application

Harvest and clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

Product Series

EXT

Brand

Zeta Plus™

3M ID

7000144884

Overall Width (Imperial)

17.8 inch

Overall Length (Imperial)

7.99 inch

Overall Length (Metric)

20.3 centimeter

Overall Width (Metric)

45.2 centimeter

Overall Diameter (Imperial)

16 inch

Overall Diameter (Metric)

40.64 centimeter

Filter Type

Depth

Grade

90ZB05A

Application

Harvest and clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

Product Series

EXT

Brand

Zeta Plus™

3M ID

7000144883

Overall Width (Imperial)

17.8 inch

Overall Length (Imperial)

2.24 inch

Overall Length (Metric)

5.7 centimeter

Overall Width (Metric)

45.2 centimeter

Overall Diameter (Imperial)

16 inch

Overall Diameter (Metric)

40.64 centimeter

Filter Type

Depth

Grade

90ZB08A

Application

Harvest and clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

Product Series

Encapsulated

Brand

Zeta Plus™

3M ID

7000144882

Overall Width (Imperial)

17.8 inch

Overall Length (Imperial)

2.24 inch

Overall Length (Metric)

5.7 centimeter

Overall Width (Metric)

45.2 centimeter

Overall Diameter (Imperial)

16 inch

Overall Diameter (Metric)

40.64 centimeter

Filter Type

Depth

Grade

90ZB05A

Application

Harvest and clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

Product Series

Encapsulated

Brand

Zeta Plus™

3M ID

7000144881

Overall Width (Imperial)

17.8 inch

Overall Length (Imperial)

2.24 inch

Overall Length (Metric)

5.7 centimeter

Overall Width (Metric)

45.2 centimeter

Overall Diameter (Imperial)

16 inch

Overall Diameter (Metric)

40.64 centimeter

Filter Type

Depth

Grade

60ZB05A

Application

Harvest and clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

Product Series

EXT

Brand

Zeta Plus™

3M ID

7000144880

Overall Width (Imperial)

17.8 inch

Overall Length (Imperial)

2.24 inch

Overall Length (Metric)

5.7 centimeter

Overall Width (Metric)

45.2 centimeter

Overall Diameter (Imperial)

16 inch

Overall Diameter (Metric)

40.64 centimeter

Filter Type

Depth

Grade

120ZB08A

Application

Harvest and clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

Product Series

Encapsulated

Brand

Zeta Plus™

Product details

The 3M Zeta Plus Encapsulated System consists of three product lines: a pilot system that is ideal for larger scale-up studies, and two systems that are designed for production scale biomanufacturing. The pilot and production systems are comprised of a filter holder, top and bottom manifolds, and the required number of capsules.

The 3M Zeta Plus Encapsulated Systems for production scale biomanufacturing feature an ergonomically designed large holder (Model #16EZB) that is pivoted between horizontal and vertical positions, allowing for convenient loading and unloading, minimal footprint during filtration, minimal fluid spills during unloading, and full utilization of the filter media.

The capsule design features a translucent plastic shell (standard capsules) for easy liquid level detection; a self-guiding locking mechanism for fast and robust capsule-to-capsule connection; and the 3M Zeta Plus depth filter media that provides excellent filtration performance.

About 3M™ Zeta Plus™ ZB Series Media

3M™ Zeta Plus™ Encapsulated Filters with ZB Series Media are optimized for secondary polishing applications in clarification of mammalian cell harvest step and for protection of downstream sterilizing grade membrane filters. Their strong positive charge provides enhanced reduction of negatively charged contaminants compared with a mechanical filtration mechanism alone. In solution cells, cellular debris, endotoxins, and nucleic acids (DNA, RNA) carry a negative charge. 3M applies the positive zeta potential to ZB filter media to create a filter matrix that enhances the capture of negatively charged contaminants for maximum filtration performance. The strong positive charge over a broad pH range makes these filters ideal for cell broth clarification and for protection of downstream membrane filters.

3M Zeta Plus Encapsulated Filters with ZB Series Media are supported with a Regulatory Support File and Certificate of Analysis to ease validation and regulatory submissions. The products are also documented in a Drug Master File (DMF) on record with the US Food and Drug Administration (FDA).

Ergonomically Designed Filter Holders

The process hardware that goes with the single use 3M Zeta Plus capsules is designed with ease of use in mind. Traditional depth filtration systems utilize lenticular style cartridge filters and a vertical filtration flow path to allow easy access to process liquids and efficient utilization of filter media. However, stacking cartridges from bottom to top can be cumbersome, and dismantling the spent cartridges is often labor intensive. Furthermore, fluid spills during the unloading process could be problematic and, in some instances, might expose the operators to the process fluids.

Recognizing the need for a depth filtration system that is fast, easy and clean, 3M designed filter holders (Model #16EZB) that can be pivoted between the horizontal position for loading and unloading the capsules and manifolds, and the vertical position for filtration. Allowing loading and unloading at waist height eliminates the need for operators to lift capsules above their heads and reduces the risk of fluid spills when handling spent capsules. The use of the vertical flow path allows for full media utilization and a small system footprint during filtration.

  • Media offers combination of single use depth filtration capsules and process hardware
  • Filter capsules contain 3M™ Zeta Plus™ ZB Series Media
  • Capsules are unique ergonomic and interlocking single-use devices that contains Zeta Plus filter media
  • Process hardware is non-fluid-contact ergonomically designed stainless-steel device that holds filter capsules
  • System reduces need for cleaning validation by eliminating stainless steel housing and cleaning step after filtration
  • Filter capsule features a lenticular design that linearly scales with filter surface area from small to large systems for many fluid challenges

Product specifications

Industries
Industries

Biopharmaceutical manufacturing

Filter Technology
Filter Technology

Adsorbent

Product Series
Product Series

Encapsulated, EXT, ZB

Grade
Grade

90ZB08A, 60ZB05A, 120ZB10A, 120ZB08A, 90ZB05A, 120ZB05A, 30ZB

Brand
Brand

Zeta Plus™

Overall Length (Imperial)
Overall Length (Imperial)

16 inch, 7.99 inch, 2.24 inch

Overall Diameter (Imperial)
Overall Diameter (Imperial)

16 inch

Overall Width (Metric)
Overall Width (Metric)

45.2 centimeter

Overall Length (Metric)
Overall Length (Metric)

40.64 centimeter, 20.3 centimeter, 5.7 centimeter

Overall Diameter (Metric)
Overall Diameter (Metric)

406.4 millimeter, 40.64 centimeter

Filter Type
Filter Type

Single-use Depth Filter

Overall Width (Imperial)
Overall Width (Imperial)

17.8 inch

Application
Application

Harvest and clarification

BP PDP

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