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3M™ Zeta Plus™ VR Series Filter Cartridge

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3M™ Zeta Plus™ VR Series Filter Cartridge
Zeta Plus™ Media Discs, V1, low res photo

About the product

We designed 3M™ Zeta Plus™ VR Series filter cartridges to help the reduction of certain viruses from biological fluids. They provide viral reduction at high flow rates in scalable cartridge configurations. Backed by our quality control testing, these products are designed for applications in biological and pharmaceutical filtration.

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Product name and IDs 3M ID Overall Diameter (Imperial) Overall Diameter (Metric) Reduction Claims End Modification Overall Height (Imperial) Overall Height (Metric) Filter Type Grade Application Filter Technology Industries Product Series Brand

3M ID

7100041865

Overall Diameter (Imperial)

12.01 inch

Overall Diameter (Metric)

30.5 centimeter

Reduction Claims

-

End Modification

-

Overall Height (Imperial)

-

Overall Height (Metric)

-

Filter Type

Depth

Grade

VR02

Application

Harvest and clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

Product Series

VR

Brand

Zeta Plus™

3M ID

7010303309

Overall Diameter (Imperial)

8 inch

Overall Diameter (Metric)

20.32 centimeter

Reduction Claims

Non Pertinent

End Modification

Double Open End

Overall Height (Imperial)

6.69 inch

Overall Height (Metric)

17 centimeter

Filter Type

Depth

Grade

VR06

Application

Harvest and clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

Product Series

VR

Brand

Zeta Plus™

Product details

The removal and/or inactivation of contaminating viruses from biotherapeutics is a regulatory requirement for helping to ensure final product safety. A range of scalable cartridge sizes and sanitary housings enables predictable performance at every stage of drug development from early stage discovery to commercial production Zeta Plus depth filtration offers an economical approach to enhance the performance of other technologies for reduction of certain types of viruses.

Our Zeta Plus VR Series filter media comprises a mixture of high surface area inorganic particles, cellulose, and a positively charged crosslinking polymer. This positive charge enhanced depth filtration combines mechanical entrapment and anion exchange for improved removal of many negatively charged containments. Depth filtration with anion exchange capacity helps protect chromatography columns or function as a prefilter to a size exclusion virus removal membrane filter.

Zeta Plus VR Series cartridges are constructed from multiple lenticular cells of opposing media discs bonded together with molded edge seals then assembled with polypropylene seals between each cell and unitized with stainless steel bands. Cartridges and sanitary housings are available in 8 inch, 12 inch, and 16 inch diameter enabling predictable scale-up to full scale production.

Pharmaceutical Grade Product

The Zeta Plus VR Series Filter Cartridges are designed for use in biological applications where virus reduction is desired. The effluent characteristics of the Zeta Plus VR Series Filter media has been tested following a number of protocols contained in the United States Pharmacopeia (USP) compendia. All components of construction including the filtration media have been tested to demonstrate compliance to USP <88> Class VI Biological Reactivity, in-vivo. These results are documented in an available Regulatory Support File.

  • With specific biological fluids, combined anion exchange and physical entrapment removal mechanisms provides an added level of viral reduction
  • Depth filtration with anion exchange capacity helps protect chromatography columns or function as a prefilter to a size exclusion virus removal membrane filter
  • Quality release testing includes a media ion exchange capacity assay
  • A range of scalable cartridge sizes and sanitary housings enables predictable performance at every stage of drug development

Product specifications

Industries
Industries

Biopharmaceutical manufacturing

Filter Technology
Filter Technology

Adsorbent

Product Series
Product Series

VR

Grade
Grade

VR02, VR06

Reduction Claims
Reduction Claims

Non Pertinent

Brand
Brand

Zeta Plus™

Overall Height (Imperial)
Overall Height (Imperial)

6.69 inch

Overall Diameter (Imperial)
Overall Diameter (Imperial)

12.01 inch, 8 inch

Overall Diameter (Metric)
Overall Diameter (Metric)

30.5 centimeter, 20.32 centimeter

End Modification
End Modification

Double Open End

Filter Type
Filter Type

Depth

Application
Application

Harvest and clarification

Overall Height (Metric)
Overall Height (Metric)

17 centimeter

BP PDP

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