3M™ Zeta Plus™ VR Series Filter Cartridge
About the product
We designed 3M™ Zeta Plus™ VR Series filter cartridges to help the reduction of certain viruses from biological fluids. They provide viral reduction at high flow rates in scalable cartridge configurations. Backed by our quality control testing, these products are designed for applications in biological and pharmaceutical filtration.
Product details
The removal and/or inactivation of contaminating viruses from biotherapeutics is a regulatory requirement for helping to ensure final product safety. A range of scalable cartridge sizes and sanitary housings enables predictable performance at every stage of drug development from early stage discovery to commercial production Zeta Plus depth filtration offers an economical approach to enhance the performance of other technologies for reduction of certain types of viruses.
Our Zeta Plus VR Series filter media comprises a mixture of high surface area inorganic particles, cellulose, and a positively charged crosslinking polymer. This positive charge enhanced depth filtration combines mechanical entrapment and anion exchange for improved removal of many negatively charged containments. Depth filtration with anion exchange capacity helps protect chromatography columns or function as a prefilter to a size exclusion virus removal membrane filter.
Zeta Plus VR Series cartridges are constructed from multiple lenticular cells of opposing media discs bonded together with molded edge seals then assembled with polypropylene seals between each cell and unitized with stainless steel bands. Cartridges and sanitary housings are available in 8 inch, 12 inch, and 16 inch diameter enabling predictable scale-up to full scale production.
Pharmaceutical Grade Product
The Zeta Plus VR Series Filter Cartridges are designed for use in biological applications where virus reduction is desired. The effluent characteristics of the Zeta Plus VR Series Filter media has been tested following a number of protocols contained in the United States Pharmacopeia (USP) compendia. All components of construction including the filtration media have been tested to demonstrate compliance to USP <88> Class VI Biological Reactivity, in-vivo. These results are documented in an available Regulatory Support File.
- With specific biological fluids, combined anion exchange and physical entrapment removal mechanisms provides an added level of viral reduction
- Depth filtration with anion exchange capacity helps protect chromatography columns or function as a prefilter to a size exclusion virus removal membrane filter
- Quality release testing includes a media ion exchange capacity assay
- A range of scalable cartridge sizes and sanitary housings enables predictable performance at every stage of drug development
Product specifications
| Industries |
Industries
Biopharmaceutical manufacturing |
| Filter Technology |
Filter Technology
Adsorbent |
| Product Series |
Product Series
VR |
| Grade |
Grade
VR02, VR06 |
| Reduction Claims |
Reduction Claims
Non Pertinent |
| Brand |
Brand
Zeta Plus™ |
| Overall Height (Imperial) |
Overall Height (Imperial)
6.69 inch |
| Overall Diameter (Imperial) |
Overall Diameter (Imperial)
12.01 inch, 8 inch |
| Overall Diameter (Metric) |
Overall Diameter (Metric)
30.5 centimeter, 20.32 centimeter |
| End Modification |
End Modification
Double Open End |
| Filter Type |
Filter Type
Depth |
| Application |
Application
Harvest and clarification |
| Overall Height (Metric) |
Overall Height (Metric)
17 centimeter |