3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule with ZB Series Media

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About the product

Recommended for secondary polishing cell clarification applications, such as DNA removal, in recombinant proteins, such as monoclonal antibodies, 3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule with ZB Series Media minimizes hold-up volume and maximize product recovery, while providing a particle free permeate solution for downstream processing.

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Product name and IDs	3M ID	Overall Width (Imperial)	Overall Length (Imperial)	Overall Length (Metric)	Overall Width (Metric)	Overall Diameter (Imperial)	Overall Diameter (Metric)	Filter Type	Grade	Application	Filter Technology	Industries	Product Series	Brand
3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule E0340FSA120ZB10A, 340 sq cm, 1/Case	3M ID 7100137819	Overall Width (Imperial) -	Overall Length (Imperial) -	Overall Length (Metric) -	Overall Width (Metric) -	Overall Diameter (Imperial) -	Overall Diameter (Metric) -	Filter Type Depth	Grade -	Application Harvest and clarification	Filter Technology Adsorbent	Industries Biopharmaceutical manufacturing	Product Series EXT	Brand Zeta Plus™
3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule E0170FSA90ZB, 170 sq cm, 1/Case	3M ID 7100085520	Overall Width (Imperial) 8.5 inch	Overall Length (Imperial) 4.06 inch	Overall Length (Metric) 10.3 centimeter	Overall Width (Metric) 21.6 centimeter	Overall Diameter (Imperial) 4.1 inch	Overall Diameter (Metric) 10.41 centimeter	Filter Type Depth	Grade 90ZB	Application Harvest and clarification	Filter Technology Adsorbent	Industries Biopharmaceutical manufacturing	Product Series Encapsulated	Brand Zeta Plus™
3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule E0170FSA120ZB10A, 170 sq cm, 1/Case	3M ID 7100078148	Overall Width (Imperial) 8.5 inch	Overall Length (Imperial) 4.06 inch	Overall Length (Metric) 10.3 centimeter	Overall Width (Metric) 21.6 centimeter	Overall Diameter (Imperial) -	Overall Diameter (Metric) -	Filter Type Depth	Grade 120ZB10A	Application Harvest and clarification	Filter Technology Adsorbent	Industries Biopharmaceutical manufacturing	Product Series Encapsulated	Brand Zeta Plus™
3M™ Zeta Plus™ Encapsulated System Scale-Up Filter CapsuleE1020FSA120ZB10A, 1020 sq cm, EFA, 1/Case	3M ID 7100049899	Overall Width (Imperial) 8.5 inch	Overall Length (Imperial) 5.98 inch	Overall Length (Metric) 15.2 centimeter	Overall Width (Metric) 21.6 centimeter	Overall Diameter (Imperial) -	Overall Diameter (Metric) -	Filter Type Depth	Grade 120ZB08A	Application Harvest and clarification	Filter Technology Adsorbent	Industries Biopharmaceutical manufacturing	Product Series Encapsulated	Brand Zeta Plus™
3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule E0340FSA90ZB, 340 sq cm, EFA, 1/Case	3M ID 7100049898	Overall Width (Imperial) -	Overall Length (Imperial) 4.06 inch	Overall Length (Metric) 10.3 centimeter	Overall Width (Metric) -	Overall Diameter (Imperial) 4.1 inch	Overall Diameter (Metric) 10.41 centimeter	Filter Type Depth	Grade -	Application Harvest and clarification	Filter Technology Adsorbent	Industries Biopharmaceutical manufacturing	Product Series ZB	Brand Zeta Plus™
3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule E1020FSA 90ZB05A, 1020 cm², EFA, 1/CS	3M ID 7100034040	Overall Width (Imperial) 8.5 inch	Overall Length (Imperial) 5.98 inch	Overall Length (Metric) 15.2 centimeter	Overall Width (Metric) 21.6 centimeter	Overall Diameter (Imperial) -	Overall Diameter (Metric) -	Filter Type Depth	Grade 90ZB05A	Application Harvest and clarification	Filter Technology Adsorbent	Industries Biopharmaceutical manufacturing	Product Series Encapsulated	Brand Zeta Plus™
3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule E0340FSA120ZB05A, 340 sq cm, 1/Case	3M ID 7100032922	Overall Width (Imperial) -	Overall Length (Imperial) -	Overall Length (Metric) -	Overall Width (Metric) -	Overall Diameter (Imperial) -	Overall Diameter (Metric) -	Filter Type Depth	Grade -	Application Harvest and clarification	Filter Technology Adsorbent	Industries Biopharmaceutical manufacturing	Product Series EXT	Brand Zeta Plus™
3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule E1020FSA90ZB, 1020 sq cm, EFA, 1/Case	3M ID 7100030470	Overall Width (Imperial) 8.5 inch	Overall Length (Imperial) 5.98 inch	Overall Length (Metric) 15.2 centimeter	Overall Width (Metric) 21.6 centimeter	Overall Diameter (Imperial) 8.5 inch	Overall Diameter (Metric) 21.59 centimeter	Filter Type Depth	Grade 90ZB	Application Harvest and clarification	Filter Technology Adsorbent	Industries Biopharmaceutical manufacturing	Product Series Encapsulated	Brand Zeta Plus™
3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule E1020FSA60ZB, 1020 sq cm, EFA, 1/Case	3M ID 7100030469	Overall Width (Imperial) 8.5 inch	Overall Length (Imperial) 5.98 inch	Overall Length (Metric) 15.2 centimeter	Overall Width (Metric) 21.6 centimeter	Overall Diameter (Imperial) 8.5 inch	Overall Diameter (Metric) 21.59 centimeter	Filter Type Depth	Grade 60ZB	Application Harvest and clarification	Filter Technology Adsorbent	Industries Biopharmaceutical manufacturing	Product Series Encapsulated	Brand Zeta Plus™
3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule E1020FSA120ZB08A, 1020 sq cm, EFA, 1/Case	3M ID 7100024302	Overall Width (Imperial) 8.5 inch	Overall Length (Imperial) 5.98 inch	Overall Length (Metric) 15.2 centimeter	Overall Width (Metric) 21.6 centimeter	Overall Diameter (Imperial) -	Overall Diameter (Metric) -	Filter Type Depth	Grade 120ZB08A	Application Harvest and clarification	Filter Technology Adsorbent	Industries Biopharmaceutical manufacturing	Product Series Encapsulated	Brand Zeta Plus™
3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule E0170FSA120ZB05A, 170 sq cm, 1/Case	3M ID 7100016810	Overall Width (Imperial) 8.5 inch	Overall Length (Imperial) 4.06 inch	Overall Length (Metric) 10.3 centimeter	Overall Width (Metric) 21.6 centimeter	Overall Diameter (Imperial) -	Overall Diameter (Metric) -	Filter Type Depth	Grade 120ZB05A	Application Harvest and clarification	Filter Technology Adsorbent	Industries Biopharmaceutical manufacturing	Product Series Encapsulated	Brand Zeta Plus™
3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule E0340FSA60ZB, 340 sq cm, 1/Case	3M ID 7010381424	Overall Width (Imperial) 8.5 inch	Overall Length (Imperial) 4.06 inch	Overall Length (Metric) 10.3 centimeter	Overall Width (Metric) 21.6 centimeter	Overall Diameter (Imperial) 4.1 inch	Overall Diameter (Metric) 10.41 centimeter	Filter Type Depth	Grade 60ZB	Application Harvest and clarification	Filter Technology Adsorbent	Industries Biopharmaceutical manufacturing	Product Series Encapsulated	Brand Zeta Plus™
3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule E0170FSA30ZB, 170 sq cm, 1/Case	3M ID 7010381420	Overall Width (Imperial) 8.5 inch	Overall Length (Imperial) 4.06 inch	Overall Length (Metric) 10.3 centimeter	Overall Width (Metric) 21.6 centimeter	Overall Diameter (Imperial) 4.1 inch	Overall Diameter (Metric) 10.41 centimeter	Filter Type Depth	Grade 30ZB	Application Harvest and clarification	Filter Technology Adsorbent	Industries Biopharmaceutical manufacturing	Product Series Encapsulated	Brand Zeta Plus™
3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule E0170FSA60ZB, 170 sq cm, 1/Case	3M ID 7010340353	Overall Width (Imperial) 8.5 inch	Overall Length (Imperial) 4.06 inch	Overall Length (Metric) 10.3 centimeter	Overall Width (Metric) 21.6 centimeter	Overall Diameter (Imperial) -	Overall Diameter (Metric) -	Filter Type Depth	Grade 60ZB	Application Harvest and clarification	Filter Technology Adsorbent	Industries Biopharmaceutical manufacturing	Product Series Encapsulated	Brand Zeta Plus™
3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule E1020FSA30ZB, 1020 sq cm, 1/Case	3M ID 7010339021	Overall Width (Imperial) -	Overall Length (Imperial) 8.27 inch	Overall Length (Metric) 21 centimeter	Overall Width (Metric) -	Overall Diameter (Imperial) 8.5 inch	Overall Diameter (Metric) 21.59 centimeter	Filter Type Depth	Grade -	Application Harvest and clarification	Filter Technology Adsorbent	Industries Biopharmaceutical manufacturing	Product Series ZB	Brand Zeta Plus™
3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule E1020FSA120ZB05A, 1020 sq cm, EFA, 1/Case	3M ID 7010339020	Overall Width (Imperial) 8.5 inch	Overall Length (Imperial) 5.98 inch	Overall Length (Metric) 15.2 centimeter	Overall Width (Metric) 21.6 centimeter	Overall Diameter (Imperial) -	Overall Diameter (Metric) -	Filter Type Depth	Grade 120ZB05A	Application Harvest and clarification	Filter Technology Adsorbent	Industries Biopharmaceutical manufacturing	Product Series Encapsulated	Brand Zeta Plus™
3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule E0340FSA30ZB, 340 sq cm, 1/Case	3M ID 7010301513	Overall Width (Imperial) 8.5 inch	Overall Length (Imperial) 4.06 inch	Overall Length (Metric) 10.3 centimeter	Overall Width (Metric) 21.6 centimeter	Overall Diameter (Imperial) 4.1 inch	Overall Diameter (Metric) 10.41 centimeter	Filter Type Depth	Grade 30ZB	Application Harvest and clarification	Filter Technology Adsorbent	Industries Biopharmaceutical manufacturing	Product Series Encapsulated	Brand Zeta Plus™
3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule E1020FSA90ZB08A, 1020 sq cm, EFA, 1/Case	3M ID 7000144879	Overall Width (Imperial) 8.5 inch	Overall Length (Imperial) 5.98 inch	Overall Length (Metric) 15.2 centimeter	Overall Width (Metric) 21.6 centimeter	Overall Diameter (Imperial) -	Overall Diameter (Metric) -	Filter Type Depth	Grade 90ZB08A	Application Harvest and clarification	Filter Technology Adsorbent	Industries Biopharmaceutical manufacturing	Product Series Encapsulated	Brand Zeta Plus™
3M™ Zeta Plus™ Encapsulated System Scale-Up Filter CapsuleE1020FSA60ZB05A, 1020 sq cm, EFA, 1/Case	3M ID 7000144878	Overall Width (Imperial) 8.5 inch	Overall Length (Imperial) 4.06 inch	Overall Length (Metric) 10.3 centimeter	Overall Width (Metric) 21.6 centimeter	Overall Diameter (Imperial) -	Overall Diameter (Metric) -	Filter Type Depth	Grade 90ZB05A	Application Harvest and clarification	Filter Technology Adsorbent	Industries Biopharmaceutical manufacturing	Product Series Encapsulated	Brand Zeta Plus™
3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule E0340FSA90ZB08A, 340 sq cm, EFA, 1/Case	3M ID 7000144877	Overall Width (Imperial) 8.5 inch	Overall Length (Imperial) 4.06 inch	Overall Length (Metric) 10.3 centimeter	Overall Width (Metric) 21.6 centimeter	Overall Diameter (Imperial) 4.1 inch	Overall Diameter (Metric) 10.41 centimeter	Filter Type Depth	Grade 90ZB08A	Application Harvest and clarification	Filter Technology Adsorbent	Industries Biopharmaceutical manufacturing	Product Series Encapsulated	Brand Zeta Plus™
3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule E0340FSA90ZB05A, 340 sq cm, EFA, 1/Case	3M ID 7000144876	Overall Width (Imperial) 8.5 inch	Overall Length (Imperial) 4.06 inch	Overall Length (Metric) 10.3 centimeter	Overall Width (Metric) 21.6 centimeter	Overall Diameter (Imperial) 4.1 inch	Overall Diameter (Metric) 10.41 centimeter	Filter Type Depth	Grade 90ZB05A	Application Harvest and clarification	Filter Technology Adsorbent	Industries Biopharmaceutical manufacturing	Product Series Encapsulated	Brand Zeta Plus™
3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule E0340FSA60ZB05A, 340 sq cm, EFA, 1/Case	3M ID 7000144875	Overall Width (Imperial) 8.5 inch	Overall Length (Imperial) 4.06 inch	Overall Length (Metric) 10.3 centimeter	Overall Width (Metric) 21.6 centimeter	Overall Diameter (Imperial) 4.1 inch	Overall Diameter (Metric) 10.41 centimeter	Filter Type Depth	Grade 60ZB05A	Application Harvest and clarification	Filter Technology Adsorbent	Industries Biopharmaceutical manufacturing	Product Series Encapsulated	Brand Zeta Plus™
3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule E0340FSA120ZB08A, 340 sq cm, 1/Case	3M ID 7000144874	Overall Width (Imperial) 8.5 inch	Overall Length (Imperial) 4.06 inch	Overall Length (Metric) 10.3 centimeter	Overall Width (Metric) 21.6 centimeter	Overall Diameter (Imperial) 4.1 inch	Overall Diameter (Metric) 10.41 centimeter	Filter Type Depth	Grade 120ZB08A	Application Harvest and clarification	Filter Technology Adsorbent	Industries Biopharmaceutical manufacturing	Product Series ZB	Brand Zeta Plus™
3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule E0170FSA90ZB05A, 170 sq cm, 1/Case	3M ID 7000144873	Overall Width (Imperial) 8.5 inch	Overall Length (Imperial) 4.06 inch	Overall Length (Metric) 10.3 centimeter	Overall Width (Metric) 21.6 centimeter	Overall Diameter (Imperial) -	Overall Diameter (Metric) -	Filter Type Depth	Grade 90ZB05A	Application Harvest and clarification	Filter Technology Adsorbent	Industries Biopharmaceutical manufacturing	Product Series Encapsulated	Brand Zeta Plus™
3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule E0170FSA60ZB05A, 170 sq cm, 1/Case	3M ID 7000144872	Overall Width (Imperial) -	Overall Length (Imperial) -	Overall Length (Metric) -	Overall Width (Metric) -	Overall Diameter (Imperial) -	Overall Diameter (Metric) -	Filter Type Depth	Grade 60ZB05A	Application Harvest and clarification	Filter Technology Adsorbent	Industries Biopharmaceutical manufacturing	Product Series ZB	Brand Zeta Plus™
3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule E0170FSA120ZB08A, 170 sq cm, 1/Case	3M ID 7000144871	Overall Width (Imperial) 8.5 inch	Overall Length (Imperial) 4.06 inch	Overall Length (Metric) 10.3 centimeter	Overall Width (Metric) 21.6 centimeter	Overall Diameter (Imperial) -	Overall Diameter (Metric) -	Filter Type Depth	Grade 120ZB08A	Application Harvest and clarification	Filter Technology Adsorbent	Industries Biopharmaceutical manufacturing	Product Series EXT	Brand Zeta Plus™
3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule E0170FSA90ZB08A, 170 sq cm, 1/Case	3M ID 7000051736	Overall Width (Imperial) -	Overall Length (Imperial) -	Overall Length (Metric) -	Overall Width (Metric) -	Overall Diameter (Imperial) -	Overall Diameter (Metric) -	Filter Type Depth	Grade 90ZB08A	Application Harvest and clarification	Filter Technology Adsorbent	Industries Biopharmaceutical manufacturing	Product Series ZB	Brand Zeta Plus™

Product details

Zeta Plus Encapsulated System Scale-Up Filter Capsule with ZB Series Media is optimized for secondary polishing applications during filtration of mammalian cell harvest fluids, clarification of high protein concentration feed streams and for optimal protection of downstream sterilizing grade membrane filters Zeta Plus Encapsulated System Scale-Up Filter Capsule with ZB Series Media are composed of inorganic filter aid, cellulose and a resin system that imparts a positive charge to the filter matrix. The single use format reduces the need for cleaning validation and minimizes filtration set up time for biopharma process development scientists.

Zeta Plus Encapsulated System Scale-Up Filter Capsule with ZB Series Media consists of two distinct layers, or "zones inch of filter media with the upstream zone more open than the downstream zone. This structure enhances the contaminant holding capacity of the filter media, since larger particles are trapped in the upper zone of the filter media and smaller particles are trapped in the lower zone, reducing premature plugging and extending service life.

Zeta Plus Encapsulated System Scale-Up Filter Capsule with ZB Series Media is optimized for clarification of mammalian cell harvest fluids and for protection of downstream sterilizing grade membrane filters. Their strong positive charge provides enhanced reduction of negatively charged contaminants compared to a mechanical filtration mechanism alone. In solution cells, cellular debris, endotoxins, and nucleic acids (DNA, RNA) carry a negative charge. 3M's application of positive zeta potential to ZB filter media creates a filter matrix that enhances the capture of negatively charged contaminants for maximum filtration performance. The strong positive charge over a broad pH range makes these filters ideal for cell broth clarification and for protection of downstream membrane filters.

Regulatory Support

Zeta Plus Encapsulated System Scale-Up Filter Capsule with ZB Series Media is manufactured in accordance with an ISO 13485 Registered Quality Management system. All filter components success fully passed the USP <88> Class VI Biological Reactivity Tests. Each filter includes certificate of quality and, to ease validation and regulatory submission. These filters are registered with the US FDA with a drug master file and a comprehensive regulatory support file is also available.

Grade Selection

The Zeta Plus Encapsulated System Scale-Up Filter Capsule with ZB Series Media is available in 6 grades. Figure below, is provided as a guide to proper grade selection based on nominal retention ratings and can be used in conjunction with the recommendations in Table below to determine the appropriate filter grade for your application. Operating conditions and the fluid being filtered impact retention performance. 3M recommends small scale pilot runs to confirm grade selection prior to scale-up. 3M's application engineering team can assist in grade selection as well as assist in on-site evaluations. Filter system optimization can also be conducted at 3M laboratory facilities.

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For more than a century, 3M has applied innovation and technology to improve customers' lives and support their business goals. From its headquarters in St. Paul, Minnesota, 3M serves industrial and commercial customers and consumers in nearly 200 countries. Across thousands of products, the 3M brand represents consistency, superior quality, and value. The 3M success begins with a culture of creative collaborat

Suitable for primary cell culture filtration or intermediate polishing applications in R&D, Process Development or manufacturing of recombinant protein drugs such as monoclonal antibodies
Made using cellulose fibers, diatomaceous earth and a binding resin that imparts a positive charge (quaternary amine), ZB grade media filters particles from process solutions through mechanical sieving and electrokinetic adsorption mechanisms
Wide range of filter pore sizes (0.1 to 4 µm) and a dual layer lenticular construction allows for optimizing filter throughput and filtrate quality
Scaleable single use filter portfolio enables using the same filtration platform process liquids volumes of 0.5 to 20,000 liters
Unique filter capsule design minimizes hold-up volume and maximizes product recovery, while reducing the need for cleaning validation; translucent plastic shell allows easy detection of the liquid level for real time monitoring of the filtration process and to minimize flush volumes

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3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule with ZB Series Media

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