3M™ LifeASSURE™ PLA Series Filter Cartridge PLA045B01CA, 10 in, .45 um,222/Spear, Silicone, 6/Case
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About the product
Our LifeASSURE™ PLA Series Filter Cartridges encompass two important design elements— multi‐zone microporous membrane and Advanced Pleat Technology — to offer prefiltration protection of final membrane filters. These filters have applications in prefiltration and clarification in the pharmaceutical, biological and bioprocess industries.
Product details
Multi-zone Microporus Membrane Construction
We incorporate our multi-zone microporous membrane technology into our LifeASSURE™ PLA Series filter cartridges. This technology allows great flexibility in creating a multi-zone membrane that offers excellent contaminant holding capacity while maintaining high retention efficiency. LifeASSURE PLA series filter membrane consists of an "open" zone on the upstream side of the membrane and a "tighter" zone on the downstream side. In effect, the open zone acts as a prefilter by capturing larger particles and colloids.
Advanced Pleat Technology Design
LifeASSURE™ PLA Series filter cartridges also feature our Advanced Pleat Technology (APT) design for extended service life. This design technology is intended to increase the useful surface area while maintaining open flow paths between media pleats.
Performance Engineered for Quality and Reliability
We manufacture LifeASSURE™ PLA Series filter cartridges using all polypropylene structural components (end caps, adapters, media support, inner core and outer cage). The 3M Purification Inc. Quality Management System is approved by an accredited registering body to the ISO 9001:2008 and ISO 13485:2003 Quality Management Systems, and the cartridges are 100% forward flow integrity tested prior to shipment. All LifeASSURE PLA Series filters are shipped with a Certificate of Quality affirming compliance with manufacturing quality specifications. Supporting Drug Master File (DMF) documentation is on file with the United States Food and Drug Administration (FDA).
Learn more about LifeASSURE™ PLA Series Filters (PDF, 315.08 Kb)
- Multi-zone microporous nylon membrane offers maximum membrane protection and increased contaminant capacity
- Advanced Pleat Technology construction allows maximum fluid and contaminant access to filter surface area for highest throughput
- 100% Integrity tested prior to release ensures consistent performance to specification
Suggested Applications
- Parenterals (SVP, LVP)
- Reagents & Buffers
- Vaccines
- Serum & Blood Fractions
- Particulate & Bioburden Reduction
- Cell Culture Fluids
- Fermenter Feed Streams
- Solvent Filtration
- High-Purity DI Water and WFI Systems
- Ophthalmics
- Orals & Topicals
Product specifications
| Industries |
Industries
Biopharmaceutical manufacturing |
| Product Form |
Product Form
Cartridge |
| ProductType |
ProductType
Pleated Membrane |
| Grade |
Grade
PLA045 |
| MicronRatingAbsolute |
MicronRatingAbsolute
0.45 absolute, @ 99.9% |
| Reduction Claims |
Reduction Claims
B. diminuta, Average LRV of 3.5 |
| OverallLengthMetric |
OverallLengthMetric
25.4 cm |
| Overall Length (Imperial) |
Overall Length (Imperial)
10 in |
| Overall Diameter (Imperial) |
Overall Diameter (Imperial)
2.76 in |
| Overall Diameter (Metric) |
Overall Diameter (Metric)
7 cm |
| End Modification |
End Modification
222 O-ring & Spear |
| Category name |
Category name
Pleated Membrane Cartridges |
| Filter Type |
Filter Type
Surface |
| ProductSeries |
ProductSeries
PLA |
| Trademark2 |
Trademark2
LifeASSURE™ |
| FilterTechnology |
FilterTechnology
Membrane |
| Application |
Application
Sterile filtration |
