3M™ Promogran™ Collagen Matrix with ORC

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About the product

As part of the Promogran Matrix Family of collagen dressings, the Promogran Collagen Matrix with ORC can improve success rates ^1-4 when used early in wound management, helping close more wounds,⁵ and reduce treatment costs.⁶ Backed by multiple Randomized Controlled Trials and meta-analysis,⁵ Promogran Matrix Family are the only collagen dressings featuring oxidized regenerated cellulose (ORC).

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Product name	Product ID	Surface Area (Imperial)	Surface Area (Metric)	Brand	Category name
3M™ Promogran™ Collagen Matrix with ORC, PG019, Hexagon 123 cm2 (19.1 sq in), 10/Ct, 4 Cts/Cs	Product ID 7100271660	Surface Area (Imperial) 19.06 in²	Surface Area (Metric) 123 cm²	Brand Promogran™	Category name Collagen Dressings
3M™ Promogran™ Collagen Matrix with ORC, PG004, Hexagon 28 cm2 (4.34 sq in), 10/Ct, 4 Cts/Cs	Product ID 7100271576	Surface Area (Imperial) 4.34 in²	Surface Area (Metric) 28 cm²	Brand Promogran™	Category name Collagen Dressings

Product details

Offering a smart choice for wound care management, the Promogran Collagen Matrix with ORC is comprised of 55% collagen and 45% ORC. In the presence of exudate, it transforms into a soft, conformable, biodegradable gel that adapts to the contours of the wound, providing complete coverage. The dressing helps create a moist wound bed and an environment that supports wound healing without the need to remove any residue during dressing changes.

Demonstrated to potentially lower the cost of treating hard-to-heal wounds⁶*

*Versus gauze dressings.

Cost-effective⁶*

Using Promogran Matrix Family of collagen dressings is cost effective^6* and has the potential to lower the total cost of treatment due to reduced nursing time and improved wound closure rates.

*Versus gauze dressings.

Increased number of wounds closed⁵*

Studies show that wounds treated using the Promogran Matrix Family of collagen dressings can significantly increase the number of wounds closed.⁵

Based on a subset meta-analysis of ten studies, wounds treated with the Promogran Matrix Family of collagen dressings are estimated to have 3.4 times greater odds of wound closure than with standard dressings. (OR = 3.4, 95% CI [1.15, 10.1] p = 0.027)⁵

*In conjunction with good clinical practice.

Prepare the wound site

Before treatment, remove dry necrotic tissue by surgical, enzymatic or autolytic debridement.

Apply the dressing

For optimal effect, apply Promogran Matrix directly to the whole wound bed. When dry, cut Promogran Matrix to accommodate the wound size. To initiate the gel forming process for wounds with low or no exudate, apply Promogran Matrix and hydrate with saline or Lactated Ringer’s solution while using the dressing tray as a container.

Secure the dressing in place

To maintain a moist wound healing environment, cover Promogran Matrix with gauze or a secondary semi-occlusive or non-occlusive dressing (non-adherent or hydropolymer). Re-treat the wound with Promogran Matrix every 72 hours depending on the amount of exudate.

For heavily exuding or infected wounds, you may need to re-treat the wound every 24 hours.

View these key evidence summaries to see how use of the Promogran™ Matrix Family of collagen dressings results in higher rates of wound closure,5* improved wound management success rates1-4 and lower total cost of treatment.6
*In conjunction with good clinical practice.

View these key evidence summaries to see how use of the Promogran™ Matrix Family of collagen dressings results in higher rates of wound closure,⁵* improved wound management success rates^1-4 and lower total cost of treatment.⁶

*In conjunction with good clinical practice.

Transforms into a soft, conformable, biodegradable gel, allowing contact with all areas of the wound.
Helps maintain a physiologically moist microenvironment that is conducive to granulation tissue formation and can significantly increase the number of wound closures.⁵* *In conjunction with good clinical practice.
Comprised of 55% collagen and 44% ORC

Suggested Applications

Management of exuding wounds, including diabetic ulcers, venous ulcers, pressure ulcers, ulcers caused by mixed vascular etiologies, full- and partial-thickness wounds, abrasions, traumatic wounds healing by secondary intention and dehisced surgical wounds.
May be used under compression therapy under the supervision of a healthcare professional.
Please refer to Instructions for Use for full application instructions.

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1. Cullen, Breda, Molly Gibson, and Lorraine Nisbet. "Early adoption of collagen/ORC therapies improves clinical outcome." Wound Repair and Regeneration 20, no. 5 (2012): A92.
2. Gottrup, Finn, Breda Mary Cullen, Tonny Karlsmark, Morten Bischoff‐Mikkelsen, Lorraine Nisbet, and Molly Camilla Gibson. "Randomized controlled trial on collagen/oxidized regenerated cellulose/silver treatment." Wound Repair and Regeneration 21, no. 2 (2013): 216-225.
3. Veves, Aristidis, Peter Sheehan, and Hau T. Pham. "A randomized, controlled trial of Promogran (a collagen/oxidized regenerated cellulose dressing) vs standard treatment in the management of diabetic foot ulcers." Archives of surgery 137, no. 7 (2002): 822-827.
4. Vin, F., L. Teot, and S. Meaume. "The healing properties of Promogran in venous leg ulcers." Journal of wound care 11, no. 9 (2002): 335-341.
5. Chowdhry, Saeed A., Yeni Nieves‐Malloure, Mark Camardo, Julie M. Robertson, and Joshua Keys. "Use of oxidised regenerated cellulose/collagen dressings versus standard of care over multiple wound types: a systematic review and meta‐analysis." International Wound Journal 19, no. 2 (2022): 241-252.
6. Snyder, Robert J., Deborah Richter, and Mary Ellen Hill. "A retrospective study of sequential therapy with advanced wound care products versus saline gauze dressings: comparing healing and cost." Ostomy wound management 56, no. 11A (2010): 9-15.

Product specifications

Brand	Brand Promogran™
Surface Area (Imperial)	Surface Area (Imperial) 4.34 in², 19.06 in²
Surface Area (Metric)	Surface Area (Metric) 28 cm², 123 cm²
Category name	Category name Collagen Dressings

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3M™ Promogran™ Collagen Matrix with ORC

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