Skip to main content

"We've detected that you're visiting from {0}. Would you like to switch languages for tailored content?"

  1. Home
  2. Purification & filtration
  3. Biopharmaceutical purification
  4. All products

3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule with ZB Series Media

Hover over image to zoom

3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule with ZB Series Media

About the product

Recommended for secondary polishing cell clarification applications, such as DNA removal, in recombinant proteins, such as monoclonal antibodies, 3M™ Zeta Plus™ Encapsulated System Scale-Up Filter Capsule with ZB Series Media minimizes hold-up volume and maximize product recovery, while providing a particle free permeate solution for downstream processing.

Product options

1-5 of Products

Select Filters to narrow your product list

Product name Product ID Catalog number Overall Width (Imperial) Overall Width (Metric) Overall Length (Imperial) Overall Length (Metric) Overall Diameter (Imperial) Overall Diameter (Metric) FilterType Grade Application Filter Technology Industries ProductSeries Brand Category name

Product ID

7100137819

Catalog number

E0340FSA 120ZB10A

Overall Width (Imperial)

-

Overall Width (Metric)

-

Overall Length (Imperial)

-

Overall Length (Metric)

-

Overall Diameter (Imperial)

-

Overall Diameter (Metric)

-

FilterType

Depth

Grade

-

Application

Harvest And Clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

ProductSeries

EXT

Brand

Zeta Plus™

Category name

Capsule Filters

Product ID

7100085520

Catalog number

E0170FSA 90ZB

Overall Width (Imperial)

8.5 in

Overall Width (Metric)

21.6 cm

Overall Length (Imperial)

4.06 in

Overall Length (Metric)

10.3 cm

Overall Diameter (Imperial)

4.1 in

Overall Diameter (Metric)

10.41 cm

FilterType

Depth

Grade

90ZB

Application

Harvest And Clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

ProductSeries

Encapsulated

Brand

Zeta Plus™

Category name

Capsule Filters

Product ID

7100078148

Catalog number

E0170FSA 120ZB10A

Overall Width (Imperial)

8.5 in

Overall Width (Metric)

21.6 cm

Overall Length (Imperial)

4.06 in

Overall Length (Metric)

10.3 cm

Overall Diameter (Imperial)

-

Overall Diameter (Metric)

-

FilterType

Depth

Grade

120ZB10A

Application

Harvest And Clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

ProductSeries

Encapsulated

Brand

Zeta Plus™

Category name

Capsule Filters

Product ID

7100049899

Catalog number

E1020FSA 120ZB10A

Overall Width (Imperial)

8.5 in

Overall Width (Metric)

21.6 cm

Overall Length (Imperial)

5.98 in

Overall Length (Metric)

15.2 cm

Overall Diameter (Imperial)

-

Overall Diameter (Metric)

-

FilterType

Depth

Grade

120ZB08A

Application

Harvest And Clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

ProductSeries

Encapsulated

Brand

Zeta Plus™

Category name

Capsule Filters

Product ID

7100049898

Catalog number

E0340FSA 90ZB

Overall Width (Imperial)

-

Overall Width (Metric)

-

Overall Length (Imperial)

4.06 in

Overall Length (Metric)

10.3 cm

Overall Diameter (Imperial)

4.1 in

Overall Diameter (Metric)

10.41 cm

FilterType

Depth

Grade

-

Application

Harvest And Clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

ProductSeries

ZB

Brand

Zeta Plus™

Category name

Capsule Filters

Product ID

7100034040

Catalog number

E1020FSA 90ZB05A

Overall Width (Imperial)

8.5 in

Overall Width (Metric)

21.6 cm

Overall Length (Imperial)

5.98 in

Overall Length (Metric)

15.2 cm

Overall Diameter (Imperial)

-

Overall Diameter (Metric)

-

FilterType

Depth

Grade

90ZB05A

Application

Harvest And Clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

ProductSeries

Encapsulated

Brand

Zeta Plus™

Category name

Capsule Filters

Product ID

7100032922

Catalog number

E0340FSA 120ZB05A

Overall Width (Imperial)

-

Overall Width (Metric)

-

Overall Length (Imperial)

-

Overall Length (Metric)

-

Overall Diameter (Imperial)

-

Overall Diameter (Metric)

-

FilterType

Depth

Grade

-

Application

Harvest And Clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

ProductSeries

EXT

Brand

Zeta Plus™

Category name

Capsule Filters

Product ID

7100030470

Catalog number

E1020FSA 90ZB

Overall Width (Imperial)

8.5 in

Overall Width (Metric)

21.6 cm

Overall Length (Imperial)

5.98 in

Overall Length (Metric)

15.2 cm

Overall Diameter (Imperial)

8.5 in

Overall Diameter (Metric)

21.59 cm

FilterType

Depth

Grade

90ZB

Application

Harvest And Clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

ProductSeries

Encapsulated

Brand

Zeta Plus™

Category name

Capsule Filters

Product ID

7100030469

Catalog number

E1020FSA 60ZB

Overall Width (Imperial)

8.5 in

Overall Width (Metric)

21.6 cm

Overall Length (Imperial)

5.98 in

Overall Length (Metric)

15.2 cm

Overall Diameter (Imperial)

8.5 in

Overall Diameter (Metric)

21.59 cm

FilterType

Depth

Grade

60ZB

Application

Harvest And Clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

ProductSeries

Encapsulated

Brand

Zeta Plus™

Category name

Capsule Filters

Product ID

7100024302

Catalog number

E1020FSA 120ZB08A

Overall Width (Imperial)

8.5 in

Overall Width (Metric)

21.6 cm

Overall Length (Imperial)

5.98 in

Overall Length (Metric)

15.2 cm

Overall Diameter (Imperial)

-

Overall Diameter (Metric)

-

FilterType

Depth

Grade

120ZB08A

Application

Harvest And Clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

ProductSeries

Encapsulated

Brand

Zeta Plus™

Category name

Capsule Filters

Product ID

7100016810

Catalog number

E0170FSA 120ZB05A

Overall Width (Imperial)

8.5 in

Overall Width (Metric)

21.6 cm

Overall Length (Imperial)

4.06 in

Overall Length (Metric)

10.3 cm

Overall Diameter (Imperial)

-

Overall Diameter (Metric)

-

FilterType

Depth

Grade

120ZB05A

Application

Harvest And Clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

ProductSeries

Encapsulated

Brand

Zeta Plus™

Category name

Capsule Filters

Product ID

7010381424

Catalog number

E0340FSA 60ZB

Overall Width (Imperial)

8.5 in

Overall Width (Metric)

21.6 cm

Overall Length (Imperial)

4.06 in

Overall Length (Metric)

10.3 cm

Overall Diameter (Imperial)

4.1 in

Overall Diameter (Metric)

10.41 cm

FilterType

Depth

Grade

60ZB

Application

Harvest And Clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

ProductSeries

Encapsulated

Brand

Zeta Plus™

Category name

Capsule Filters

Product ID

7010381420

Catalog number

E0170FSA 30ZB

Overall Width (Imperial)

8.5 in

Overall Width (Metric)

21.6 cm

Overall Length (Imperial)

4.06 in

Overall Length (Metric)

10.3 cm

Overall Diameter (Imperial)

4.1 in

Overall Diameter (Metric)

10.41 cm

FilterType

Depth

Grade

30ZB

Application

Harvest And Clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

ProductSeries

Encapsulated

Brand

Zeta Plus™

Category name

Capsule Filters

Product ID

7010340353

Catalog number

E0170FSA 60ZB

Overall Width (Imperial)

8.5 in

Overall Width (Metric)

21.6 cm

Overall Length (Imperial)

4.06 in

Overall Length (Metric)

10.3 cm

Overall Diameter (Imperial)

-

Overall Diameter (Metric)

-

FilterType

Depth

Grade

60ZB

Application

Harvest And Clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

ProductSeries

Encapsulated

Brand

Zeta Plus™

Category name

Capsule Filters

Product ID

7010339021

Catalog number

E1020FSA 30ZB

Overall Width (Imperial)

-

Overall Width (Metric)

-

Overall Length (Imperial)

8.27 in

Overall Length (Metric)

21 cm

Overall Diameter (Imperial)

8.5 in

Overall Diameter (Metric)

21.59 cm

FilterType

Depth

Grade

-

Application

Harvest And Clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

ProductSeries

ZB

Brand

Zeta Plus™

Category name

Capsule Filters

Product ID

7010339020

Catalog number

E1020FSA 120ZB05A

Overall Width (Imperial)

8.5 in

Overall Width (Metric)

21.6 cm

Overall Length (Imperial)

5.98 in

Overall Length (Metric)

15.2 cm

Overall Diameter (Imperial)

-

Overall Diameter (Metric)

-

FilterType

Depth

Grade

120ZB05A

Application

Harvest And Clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

ProductSeries

Encapsulated

Brand

Zeta Plus™

Category name

Capsule Filters

Product ID

7010301513

Catalog number

E0340FSA 30ZB

Overall Width (Imperial)

8.5 in

Overall Width (Metric)

21.6 cm

Overall Length (Imperial)

4.06 in

Overall Length (Metric)

10.3 cm

Overall Diameter (Imperial)

4.1 in

Overall Diameter (Metric)

10.41 cm

FilterType

Depth

Grade

30ZB

Application

Harvest And Clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

ProductSeries

Encapsulated

Brand

Zeta Plus™

Category name

Capsule Filters

Product ID

7000144879

Catalog number

E1020FSA 90ZB08A

Overall Width (Imperial)

8.5 in

Overall Width (Metric)

21.6 cm

Overall Length (Imperial)

5.98 in

Overall Length (Metric)

15.2 cm

Overall Diameter (Imperial)

-

Overall Diameter (Metric)

-

FilterType

Depth

Grade

90ZB08A

Application

Harvest And Clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

ProductSeries

Encapsulated

Brand

Zeta Plus™

Category name

Capsule Filters

Product ID

7000144878

Catalog number

E1020FSA 60ZB05A

Overall Width (Imperial)

8.5 in

Overall Width (Metric)

21.6 cm

Overall Length (Imperial)

4.06 in

Overall Length (Metric)

10.3 cm

Overall Diameter (Imperial)

-

Overall Diameter (Metric)

-

FilterType

Depth

Grade

90ZB05A

Application

Harvest And Clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

ProductSeries

Encapsulated

Brand

Zeta Plus™

Category name

Capsule Filters

Product ID

7000144877

Catalog number

E0340FSA 90ZB08A

Overall Width (Imperial)

8.5 in

Overall Width (Metric)

21.6 cm

Overall Length (Imperial)

4.06 in

Overall Length (Metric)

10.3 cm

Overall Diameter (Imperial)

4.1 in

Overall Diameter (Metric)

10.41 cm

FilterType

Depth

Grade

90ZB08A

Application

Harvest And Clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

ProductSeries

Encapsulated

Brand

Zeta Plus™

Category name

Capsule Filters

Product ID

7000144876

Catalog number

E0340FSA 90ZB05A

Overall Width (Imperial)

8.5 in

Overall Width (Metric)

21.6 cm

Overall Length (Imperial)

4.06 in

Overall Length (Metric)

10.3 cm

Overall Diameter (Imperial)

4.1 in

Overall Diameter (Metric)

10.41 cm

FilterType

Depth

Grade

90ZB05A

Application

Harvest And Clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

ProductSeries

Encapsulated

Brand

Zeta Plus™

Category name

Capsule Filters

Product ID

7000144875

Catalog number

E0340FSA 60ZB05A

Overall Width (Imperial)

8.5 in

Overall Width (Metric)

21.6 cm

Overall Length (Imperial)

4.06 in

Overall Length (Metric)

10.3 cm

Overall Diameter (Imperial)

4.1 in

Overall Diameter (Metric)

10.41 cm

FilterType

Depth

Grade

60ZB05A

Application

Harvest And Clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

ProductSeries

Encapsulated

Brand

Zeta Plus™

Category name

Capsule Filters

Product ID

7000144874

Catalog number

E0340FSA 120ZB08A

Overall Width (Imperial)

8.5 in

Overall Width (Metric)

21.6 cm

Overall Length (Imperial)

4.06 in

Overall Length (Metric)

10.3 cm

Overall Diameter (Imperial)

4.1 in

Overall Diameter (Metric)

10.41 cm

FilterType

Depth

Grade

120ZB08A

Application

Harvest And Clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

ProductSeries

ZB

Brand

Zeta Plus™

Category name

Capsule Filters

Product ID

7000144873

Catalog number

E0170FSA 90ZB05A

Overall Width (Imperial)

8.5 in

Overall Width (Metric)

21.6 cm

Overall Length (Imperial)

4.06 in

Overall Length (Metric)

10.3 cm

Overall Diameter (Imperial)

-

Overall Diameter (Metric)

-

FilterType

Depth

Grade

90ZB05A

Application

Harvest And Clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

ProductSeries

Encapsulated

Brand

Zeta Plus™

Category name

Capsule Filters

Product ID

7000144872

Catalog number

E0170FSA 60ZB05A

Overall Width (Imperial)

-

Overall Width (Metric)

-

Overall Length (Imperial)

-

Overall Length (Metric)

-

Overall Diameter (Imperial)

-

Overall Diameter (Metric)

-

FilterType

Depth

Grade

60ZB05A

Application

Harvest And Clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

ProductSeries

ZB

Brand

Zeta Plus™

Category name

Capsule Filters

Product ID

7000144871

Catalog number

E0170FSA 120ZB08A

Overall Width (Imperial)

8.5 in

Overall Width (Metric)

21.6 cm

Overall Length (Imperial)

4.06 in

Overall Length (Metric)

10.3 cm

Overall Diameter (Imperial)

-

Overall Diameter (Metric)

-

FilterType

Depth

Grade

120ZB08A

Application

Harvest And Clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

ProductSeries

EXT

Brand

Zeta Plus™

Category name

Capsule Filters

Product ID

7000051736

Catalog number

E0170FSA 90ZB08A

Overall Width (Imperial)

-

Overall Width (Metric)

-

Overall Length (Imperial)

-

Overall Length (Metric)

-

Overall Diameter (Imperial)

-

Overall Diameter (Metric)

-

FilterType

Depth

Grade

90ZB08A

Application

Harvest And Clarification

Filter Technology

Adsorbent

Industries

Biopharmaceutical manufacturing

ProductSeries

ZB

Brand

Zeta Plus™

Category name

Capsule Filters

Product details

Zeta Plus Encapsulated System Scale-Up Filter Capsule with ZB Series Media is optimized for secondary polishing applications during filtration of mammalian cell harvest fluids, clarification of high protein concentration feed streams and for optimal protection of downstream sterilizing grade membrane filters Zeta Plus Encapsulated System Scale-Up Filter Capsule with ZB Series Media are composed of inorganic filter aid, cellulose and a resin system that imparts a positive charge to the filter matrix. The single use format reduces the need for cleaning validation and minimizes filtration set up time for biopharma process development scientists.

Zeta Plus Encapsulated System Scale-Up Filter Capsule with ZB Series Media consists of two distinct layers, or "zones inch of filter media with the upstream zone more open than the downstream zone. This structure enhances the contaminant holding capacity of the filter media, since larger particles are trapped in the upper zone of the filter media and smaller particles are trapped in the lower zone, reducing premature plugging and extending service life.

Zeta Plus Encapsulated System Scale-Up Filter Capsule with ZB Series Media is optimized for clarification of mammalian cell harvest fluids and for protection of downstream sterilizing grade membrane filters. Their strong positive charge provides enhanced reduction of negatively charged contaminants compared to a mechanical filtration mechanism alone. In solution cells, cellular debris, endotoxins, and nucleic acids (DNA, RNA) carry a negative charge. 3M's application of positive zeta potential to ZB filter media creates a filter matrix that enhances the capture of negatively charged contaminants for maximum filtration performance. The strong positive charge over a broad pH range makes these filters ideal for cell broth clarification and for protection of downstream membrane filters.

Regulatory Support

Zeta Plus Encapsulated System Scale-Up Filter Capsule with ZB Series Media is manufactured in accordance with an ISO 13485 Registered Quality Management system. All filter components success fully passed the USP <88> Class VI Biological Reactivity Tests. Each filter includes certificate of quality and, to ease validation and regulatory submission. These filters are registered with the US FDA with a drug master file and a comprehensive regulatory support file is also available.

Grade Selection

The Zeta Plus Encapsulated System Scale-Up Filter Capsule with ZB Series Media is available in 6 grades. Figure below, is provided as a guide to proper grade selection based on nominal retention ratings and can be used in conjunction with the recommendations in Table below to determine the appropriate filter grade for your application. Operating conditions and the fluid being filtered impact retention performance. 3M recommends small scale pilot runs to confirm grade selection prior to scale-up. 3M's application engineering team can assist in grade selection as well as assist in on-site evaluations. Filter system optimization can also be conducted at 3M laboratory facilities.

A History of Innovation

For more than a century, 3M has applied innovation and technology to improve customers' lives and support their business goals. From its headquarters in St. Paul, Minnesota, 3M serves industrial and commercial customers and consumers in nearly 200 countries. Across thousands of products, the 3M brand represents consistency, superior quality, and value. The 3M success begins with a culture of creative collaborat

  • Suitable for primary cell culture filtration or intermediate polishing applications in R&D, Process Development or manufacturing of recombinant protein drugs such as monoclonal antibodies
  • Made using cellulose fibers, diatomaceous earth and a binding resin that imparts a positive charge (quaternary amine), ZB grade media filters particles from process solutions through mechanical sieving and electrokinetic adsorption mechanisms
  • Wide range of filter pore sizes (0.1 to 4 µm) and a dual layer lenticular construction allows for optimizing filter throughput and filtrate quality
  • Scaleable single use filter portfolio enables using the same filtration platform process liquids volumes of 0.5 to 20,000 liters
  • Unique filter capsule design minimizes hold-up volume and maximizes product recovery, while reducing the need for cleaning validation; translucent plastic shell allows easy detection of the liquid level for real time monitoring of the filtration process and to minimize flush volumes

Product specifications

Industries
Industries

Biopharmaceutical manufacturing

OverallLengthImperial
OverallLengthImperial

4.06 in, 5.98 in

Filter Technology
Filter Technology

Adsorbent

OverallWidthMetric
OverallWidthMetric

21.6 cm

Product Series
Product Series

EXT, ZB, Encapsulated

categoryName
categoryName

Capsule Filters

OverallLengthMetric
OverallLengthMetric

10.3 cm

ProductSeries
ProductSeries

Encapsulated

Category name
Category name

Capsule Filters

Trademark2
Trademark2

Zeta Plus™

Catalog number
Catalog number

E1020FSA 90ZB05A, E0170FSA 60ZB05A, E0340FSA 60ZB05A, E0340FSA 90ZB05A, E0170FSA 90ZB08A, E0170FSA 90ZB05A, E0340FSA 120ZB10A, E0340FSA 120ZB08A, E0170FSA 120ZB10A, E1020FSA 120ZB08A, E0170FSA 30ZB, E1020FSA 90ZB08A, E0340FSA 90ZB08A, E1020FSA 60ZB05A, E0340FSA 120ZB05A, E0340FSA 30ZB, E1020FSA 120ZB10A, E1020FSA 120ZB05A, E1020FSA 30ZB

Grade
Grade

120ZB05A, 90ZB05A, 120ZB08A, 60ZB05A, 90ZB08A, 120ZB10A, 30ZB

Brand
Brand

Zeta Plus™

FilterType
FilterType

Depth

Overall Length (Imperial)
Overall Length (Imperial)

4.06 in, 5.98 in, 8.27 in

Overall Diameter (Imperial)
Overall Diameter (Imperial)

4.1 in, 8.5 in

Overall Width (Metric)
Overall Width (Metric)

21.6 cm

Overall Length (Metric)
Overall Length (Metric)

15.2 cm, 10.3 cm, 21 cm

OverallWidthImperial
OverallWidthImperial

8.5 in

GLBL_CAT_NBR
GLBL_CAT_NBR

E0170FSA 120ZB05A, E0170FSA 120ZB08A

Overall Diameter (Metric)
Overall Diameter (Metric)

10.41 cm, 21.59 cm

Filter Type
Filter Type

Depth

FilterTechnology
FilterTechnology

Adsorbent

Overall Width (Imperial)
Overall Width (Imperial)

8.5 in

Application
Application

Harvest And Clarification

Ask an expert

How did you hear about us? (check all that apply)