3M™ Zeta Plus™ BC Series Filter Capsule with LP Series Media
About the product
We designed the 3M™ Zeta Plus™ BC Series Filter Capsules with LP Series Media for manufacturing of biological products and have a reduced potential of yielding false positives in drug product endotoxin testing resulting from 1,3 Beta-glucan interference in LAL assays. Using the same media, BC25 Laboratory capsules are ideal for assessing filtration media grades using low challenge fluid volumes.
Product details
Our 3M™ Zeta Plus™ LP Series filter media comprises of a mixture of high surface area inorganic particles, cellulose, and a positively charged crosslinking polymer. Designed for relatively low organic extractable levels by aggressively extracting the cellulose fibers. The combination of filtration efficiency and throughput results from the balance between porosity, depth, and the relatively low level anion exchange capacity: removing some negatively charged soluble contaminants and sub-micron particles via anion exchange, and larger particles by mechanical sieving.
Our BC25 laboratory capsule is ideal for optimizing the filtration performance for each drug process by effectively screening the available single layer media options. A scalable range of cartridges enables predictable performance at every stage of drug development from early stage discovery to commercial production.
Pharmaceutical Grade Product
We designed the Zeta Plus LP Series media for use in blood fractionation and biological applications. The effluent characteristics of the Zeta Plus LP Series filter media has been tested following a number of protocols contained in the United States Pharmacopeia (USP) compendia. All components of construction including the filtration media have been tested to demonstrate compliance to USP <88> Class VI Biological Reactivity, in-vivo. These results are documented in an available Regulatory Support File.
The Zeta Plus LP Series media has a reduced potential of yielding false positives in product endotoxin testing resulting from 1,3 Beta-glucan interference in LAL (Endotoxin) assays.
Scalable Single-use Capsules
The BC25 laboratory capsule with 25 cm2 filter media is ideal for media grade screening using small liquid volumes.
Filter cartridges and sanitary housings are available in 8 inch, 12 inch, and 16 inch diameters, with surface areas ranging from 650 cm2 to 3.9 m2 per cartridge, enabling predictable scale-up and full scale production.
- 3M™ Zeta Plus™ BC Series Filter Capsules with LP Series Media are designed for manufacturing of biological products such as blood and blood products, vaccines, allergen extracts, and cellular harvests
- Reduced potential of 1,3 Beta-glucan interference in product endotoxin testing
- BC25 Laboratory capsules contain same media as in production scale systems
- Full range of scalable single-use cartridges enables predictable performance from the laboratory to commercial production
Product specifications
| Industries |
Industries
Biopharmaceutical manufacturing |
| Filter Technology |
Filter Technology
Adsorbent |
| Product Series |
Product Series
BC, Encapsulated |
| Grade |
Grade
50LP, 30LP, 60LP |
| Brand |
Brand
Zeta Plus™ |
| Overall Diameter (Imperial) |
Overall Diameter (Imperial)
2.63 inch |
| Overall Width (Metric) |
Overall Width (Metric)
25 centimeter, 45.2 centimeter |
| Overall Length (Imperial) |
Overall Length (Imperial)
7.99 inch |
| Overall Length (Metric) |
Overall Length (Metric)
20.3 centimeter |
| Overall Diameter (Metric) |
Overall Diameter (Metric)
66.8 millimeter |
| End Modification |
End Modification
Luer, Sanitary Fitting |
| Filter Type |
Filter Type
Depth |
| Overall Width (Imperial) |
Overall Width (Imperial)
9.84 inch, 17.8 inch |
| Application |
Application
Harvest and clarification |