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  1. 3M™ Emphaze™ AEX Hybrid Purifier

3M™ Emphaze™ AEX Series Hybrid Purifier BV8, EMP303AEX020R, Sanitary,2/Case

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3M™ Emphaze™ AEX Series Hybrid Purifier BV8, EMP303AEX020R, Sanitary,2/Case

About the product

3M™ Emphaze AEX Hybrid Purifier is our single-use sterilisable and sanitisable. The all-synthetic purification media that contains a Q-functional anion exchange media and a fine particle and bioburden reduction membrane.

Details

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  • Industries : Biopharmaceutical manufacturing
  • Net Weight (Metric) : 77 g
  • Filter Technology : Anion exchange chromatography
  • Micron Rating : 0.2 μm
  • Product Series : AEX
  • Flow Rate (Metric) : 8 ml/min
  • Flow Rate (Imperial) : 0.002 gal/min
  • Brand : Emphaze™
  • Overall Height (Imperial) : 3.46 in
  • Overall Diameter (Imperial) : 3.03 in
  • Overall Diameter (Metric) : 7.7 cm
  • End Modification : 3/4 in Sanitary Connectors
  • Category name : Chromatography Filters
  • Filter Type : Single Use
  • Application : Harvest And Clarification
  • Overall Height (Metric) : 8.8 cm

Product details

Remove impurities in biopharmaceutical process streams such as DNA, host cell proteins (HCP) and viruses with our all-synthetic, single use 3M™ Emphaze AEX Hybrid Purifier. The composite purification media is comprised of three primary components: anion exchange nonwoven, microporous membrane, and membrane support. The anion exchange media is composed of four layers of polypropylene nonwoven with a covalently attached quaternary ammonium functional polymer. The bioburden reduction membrane is a highly asymmetric polyamide membrane which has nine zones of decreasing pore size, spanning approximately a 20 X range, and terminating with a 0.2 μm rated qualifying layer. This is followed by a polypropylene nonwoven used as a support layer in the capsule. Capsules There are two primary capsule configurations for the Emphaze AEX Hybrid Purifier, Laboratory and Scale-up capsules: - The Laboratory capsule (BV8) has an 8ml bed volume - The Scale-up capsules are constructed from a lenticular media cell design having bed volumes of 120 mls and 360 mls (BV 120 and BV 360 respectively) - The Production capsules are scaled to meet your manufacturing requirements and utilise manifolds in a holder for ease of use A full support package is available for 3M Emphaze AEX Hybrid Purifiers. This package includes Installation and Operation Guides, a Certificate of Quality and a Regulatory Support File.
  • All-synthetic, highly functionalised media (contains no naturally-derived materials)
  • Asymmetric membrane ending with a 0.2 µm bioburden reduction zone
  • Excellent mAb recovery, often equal to or greater than 95%
  • Substantial turbidity, DNA, HCP and bioburden reduction
  • Reduced surface area requirement of the downstream sterilising grade membrane
  • May offer differentiated protection to the protein A column for enhanced contaminant clearance performance
  • All product components comply with United States Pharmacopeia (USP) <88> Class VI 70°C Biological Reactivity Tests, in vivo
  • Autoclavable

Suggested Applications

  • Use for the clarification of mammalian cell cultures and to optimise downstream processes for monoclonal antibodies (mAbs)

Product specifications

Industries
Industries

Biopharmaceutical manufacturing

Net Weight (Metric)
Net Weight (Metric)

77 g

Filter Technology
Filter Technology

Anion exchange chromatography

Micron Rating
Micron Rating

0.2 μm

Product Series
Product Series

AEX

Flow Rate (Metric)
Flow Rate (Metric)

8 ml/min

Flow Rate (Imperial)
Flow Rate (Imperial)

0.002 gal/min

Brand
Brand

Emphaze™

Overall Height (Imperial)
Overall Height (Imperial)

3.46 in

Overall Diameter (Imperial)
Overall Diameter (Imperial)

3.03 in

Overall Diameter (Metric)
Overall Diameter (Metric)

7.7 cm

End Modification
End Modification

3/4 in Sanitary Connectors

Category name
Category name

Chromatography Filters

Filter Type
Filter Type

Single Use

Application
Application

Harvest And Clarification

Overall Height (Metric)
Overall Height (Metric)

8.8 cm

Resources

1-1 of 1 Resource

Emphaze(TM) AEX

Emphaze(TM) AEX

Emphaze(TM) AEX

View Document

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