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Your first step is wound bed prep

Appropriate preparation is vital for optimal patient outcomes

Promogran Prisma™ Collagen Matrix with ORC and Silver and ActiV.A.C.™ Therapy System Group Image for Wound Bed Prep

A powerful pair for wound bed prep

3M™ Promogran Prisma™ Collagen Matrix with ORC and Silver

  • Exclusive pairing of collagen with ORC helps reduce elastase activity to promote healing1,2
  • Inactivate harmful proteases and protect growth factors3
  • Due to the antibacterial properties of silver,  Promogran Prisma Matrix is known to provide an effective antibacterial barrier against common wound pathogens in vitro4

Solventum™ ActiV.A.C.™ Therapy System with Solventum™ V.A.C.® Granufoam™ Dressing 

Creates macrostrain and microstrain, removes exudate and infectious  material, reduces edema and promotes granulation tissue formation. 

By integrating advanced therapies like Promogran Prisma Matrix and ActiV.A.C. Therapy System, clinicians can address complex wound types, including diabetic ulcers, venous leg ulcers, pressure injuries, surgical wounds and more, showing benefits such as:

  • Faster time to granulation tissue development
  • Reduced wound area and volume
  • Improved wound bed preparation outcomes4,5
3M™ Promogran Prisma™ Collagen Matrix with ORC and Silver Group Shot for Wound Bed Prep

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NOTE: Specific indications, contraindications, warnings, precautions and safety information exist for these products and therapies. Please consult a clinician and product instructions for use prior to application. Rx only

References:

*Mulder G, Lavery LA, Marston WA et al (2024) Skin substitutes for the management of hard-to-heal wounds. London: Wounds International. Available to download from: www.woundsinternational.com

  1. Cullen B, Watt PW, Lundqvist C, Silcock D, Schmidt RJ, Bogan D, Light ND. The role of oxidised regenerated cellulose/collagen in chronic wound repair and its potential mechanism of action. Int J Biochem Cell Biol 2002; 34(12): 1544-1556.
  2. Serena T, Cullen B, Bayliff S, Gibson M, DeMarco D, Galbraith J, Le N, Mancinelli M, Sabo M, Samies J. Protease Activity Levels Associated with Healing Status of Chronic Wounds. Poster presented at: Wounds UK Annual Conference, Harrogate, UK, 2011.
  3. Gottrup F, Cullen B, Karlsmark T, Bischoff-Mikkelsen M, Nisbet L, Gibson M. Randomized controlled trial on collagen/oxidized regenerated cellulose /silver treatment. Wound Repair & Regeneration 2013; 21: 1-10.
  4. Bourdillon KA, Delury C, Cullen B. Biofilms and delayed healing – an in vitro evaluation of silver and iodine containing dressings and their effect on bacterial and human cells. International Wound Journal 2017. ISSN 1742-4801.
  5. Klein R, Desvigne MN, Greenstein E, et al. Use of silver collagen oxidized regenerated cellulose dressings in conjunction with negative pressure wound therapy: expert panel consensus recommendations. Wounds. 2024;36(8):263-273. doi:10.25270/wnds/2402
  6. Hou Y, Griffin L. Comparative effectiveness of negative pressure wound therapy with and without oxidized regenerated cellulose (ORC) collagen/silver-ORC dressing. Poster presented at: SAWC, National Harbor, MD, 2023.