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Your first step is wound bed prep

Appropriate preparation is vital for optimal patient outcomes

Wound Bed Prep Composite Image with Promogran Prisma Matrix w/Burst

A powerful pair for wound bed prep

3M™ Promogran Prisma™ Collagen Matrix with ORC and Silver

  • Exclusive pairing of collagen with ORC helps reduce elastase activity to promote healing1,2
  • Supports granulation tissue formation, epithelialization, and wound healing.
  • Due to the antibacterial properties of silver,  Promogran Prisma Matrix is known to provide an effective antibacterial barrier against common wound pathogens in vitro3

Solventum™ ActiV.A.C.™ Therapy System 

  • Draws wound edges together
  • Removes exudate and infectious material
  • Promotes granulation tissue formation and perfusion

Combining these Advanced Therapies

Promogran Prisma Matrix can be used in combination with the ActiV.A.C. Therapy Unit with either Solventum™ V.A.C.® Drape or Solventum™ Dermatac™ Drape and the associated dressings:

  • Solventum™ V.A.C.® Peel and Place Dressings
  • Solventum™ V.A.C.® Granufoam™ Dressings
  • Solventum™ V.A.C.® Simplace™ Dressings

This allows clinicians to address complex wound types, including diabetic ulcers, venous leg ulcers, pressure injuries, surgical wounds and more, showing benefits such as:

  • Faster time to granulation tissue development4,5
  • Reduced wound area and volume4,5
  • Improved wound bed preparation outcomes4,5
  • Approved indication for use with V.A.C.® Peel and Place Dressing
3M™ Promogran Prisma™ Collagen Matrix with ORC and Silver Group Shot for Wound Bed Prep

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NOTE: Specific indications, contraindications, warnings, precautions and safety information exist for these products and therapies. Please consult a clinician and product instructions for use prior to application. Rx only.

References:

  1. Cullen B, Watt PW, Lundqvist C, Silcock D, Schmidt RJ, Bogan D, Light ND. The role of oxidised regenerated cellulose/collagen in chronic wound repair and its potential mechanism of action. Int J Biochem Cell Biol 2002; 34(12): 1544-1556.
  2. Serena T, Cullen B, Bayliff S, Gibson M, DeMarco D, Galbraith J, Le N, Mancinelli M, Sabo M, Samies J. Protease Activity Levels Associated with Healing Status of Chronic Wounds. Poster presented at: Wounds UK Annual Conference, Harrogate, UK, 2011.
  3. Bourdillon KA, Delury C, Cullen B. Biofilms and delayed healing – an in vitro evaluation of silver and iodine containing dressings and their effect on bacterial and human cells. International Wound Journal 2017. ISSN 1742-4801.
  4. Klein R, Desvigne MN, Greenstein E, et al. Use of silver collagen oxidized regenerated cellulose dressings in conjunction with negative pressure wound therapy: expert panel consensus recommendations. Wounds. 2024;36(8):263-273. doi:10.25270/wnds/2402.
  5. Hou Y, Griffin L. Comparative Effectiveness of Negative Pressure Wound Therapy with and Without Oxidized Regenerated Cellulose/Collagen/Silver-ORC Dressing. Adv Wound Care (New Rochelle). 2025; 14(6): 285-294.
  6. Atkin L, Bucko Z, Conde Montero E, et al. Implementing TIMERS: the race against hard-to-heal wounds. J Wound Care. 2019;23 (Suppl 3a): S1-S50.