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3M™ Emphaze™ AEX Series Hybrid Purifier BV5600R, EMP770AEX020R, 16 in,1/Case

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3M™ Emphaze™ AEX Series Hybrid Purifier BV5600R, EMP770AEX020R, 16 in,1/Case
3M™ Emphaze™ AEX Hybrid Purifier Family

About the product

3M™ Emphaze AEX Hybrid Purifier is our single-use sterilisable and sanitisable. The all-synthetic purification media that contains a Q-functional anion exchange media and a fine particle and bioburden reduction membrane.

Details

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  • FlowRateMetric : 4700 ml/min
  • Industries : Biopharmaceutical manufacturing
  • Micron Rating : 0.2 μm
  • OverallDiameterImperial : 17.8 in
  • Product Series : Emphaze AEX
  • EndModification : 1 1/2 in Sanitary Connectors
  • categoryName : Chromatography Filters
  • Brand : Emphaze™
  • Overall Height (Imperial) : 7.99 in
  • OverallHeightMetric : 20.3 cm
  • FlowRateImperial : 1.034 gal/min
  • NetWeightMetric : 9.5 kg
  • Overall Diameter (Metric) : 45.2 cm
  • Filter Type : Single Use
  • FilterTechnology : Anion exchange chromatography
  • Application : Harvest And Clarification

Product details

Remove impurities in biopharmaceutical process streams such as DNA, host cell proteins (HCP) and viruses with our all-synthetic, single use 3M™ Emphaze AEX Hybrid Purifier. The composite purification media is comprised of three primary components: anion exchange nonwoven, microporous membrane, and membrane support. The anion exchange media is composed of four layers of polypropylene nonwoven with a covalently attached quaternary ammonium functional polymer. The bioburden reduction membrane is a highly asymmetric polyamide membrane which has nine zones of decreasing pore size, spanning approximately a 20 X range, and terminating with a 0.2 μm rated qualifying layer. This is followed by a polypropylene nonwoven used as a support layer in the capsule. Capsules There are two primary capsule configurations for the Emphaze AEX Hybrid Purifier, Laboratory and Scale-up capsules: - The Laboratory capsule (BV8) has an 8ml bed volume - The Scale-up capsules are constructed from a lenticular media cell design having bed volumes of 120 mls and 360 mls (BV 120 and BV 360 respectively) - The Production capsules are scaled to meet your manufacturing requirements and utilise manifolds in a holder for ease of use A full support package is available for 3M Emphaze AEX Hybrid Purifiers. This package includes Installation and Operation Guides, a Certificate of Quality and a Regulatory Support File.
  • All-synthetic, highly functionalised media (contains no naturally-derived materials)
  • Asymmetric membrane ending with a 0.2 µm bioburden reduction zone
  • Excellent mAb recovery, often equal to or greater than 95%
  • Substantial turbidity, DNA, HCP and bioburden reduction
  • Reduced surface area requirement of the downstream sterilising grade membrane
  • May offer differentiated protection to the protein A column for enhanced contaminant clearance performance
  • All product components comply with United States Pharmacopeia (USP) <88> Class VI 70°C Biological Reactivity Tests, in vivo
  • Autoclavable

Suggested Applications

  • Use for the clarification of mammalian cell cultures and to optimise downstream processes for monoclonal antibodies (mAbs)

Product specifications

FlowRateMetric
FlowRateMetric

4700 ml/min

Industries
Industries

Biopharmaceutical manufacturing

Micron Rating
Micron Rating

0.2 μm

OverallDiameterImperial
OverallDiameterImperial

17.8 in

Product Series
Product Series

Emphaze AEX

EndModification
EndModification

1 1/2 in Sanitary Connectors

categoryName
categoryName

Chromatography Filters

Brand
Brand

Emphaze™

Overall Height (Imperial)
Overall Height (Imperial)

7.99 in

OverallHeightMetric
OverallHeightMetric

20.3 cm

FlowRateImperial
FlowRateImperial

1.034 gal/min

NetWeightMetric
NetWeightMetric

9.5 kg

Overall Diameter (Metric)
Overall Diameter (Metric)

45.2 cm

Filter Type
Filter Type

Single Use

FilterTechnology
FilterTechnology

Anion exchange chromatography

Application
Application

Harvest And Clarification

Resources

1-1 of 1 Resource

Emphaze(TM) AEX

Emphaze(TM) AEX

Emphaze(TM) AEX

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