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3M™ Polisher ST

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3M™ Polisher ST
3M(TM) Polisher ST family
3M(TM) Polisher ST family
3M(TM) Polisher ST family

About the product

The 3M™ Polisher ST is a fully encapsulated single-use anion exchange (AEX) product. It is intended to reduce host cell protein, viruses, and other negatively charged contaminants in a flow-through polishing chromatography mode in biopharmaceutical process streams. The 3M™ Polisher ST is a synthetic, hybrid purifier containing two complementary AEX-functional media: a quaternary ammonium (“Q”) functional nonwoven and a guanidinium-functional membrane.

Product options

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Product name Product ID Overall Diameter (Imperial) Overall Diameter (Metric) Overall Height (Imperial) Overall Height (Metric) End Modification Micron Rating Flow Rate (Imperial) Flow Rate (Metric) Filter Type Net Weight (Metric) Application Filter Technology Industries Product Series Category name

Product ID

7100228761

Overall Diameter (Imperial)

1.69 in

Overall Diameter (Metric)

4.3 cm

Overall Height (Imperial)

2.32 in

Overall Height (Metric)

5.9 cm

End Modification

Luer Lock

Micron Rating

0.8 μm

Flow Rate (Imperial)

0.001 gal/min

Flow Rate (Metric)

4 ml/min

Filter Type

Single Use

Net Weight (Metric)

15.5 g

Application

Anion exchange

Filter Technology

Anion exchange chromatography

Industries

Biopharmaceutical manufacturing

Product Series

Polisher ST

Category name

Chromatography Filters

Product ID

7100228760

Overall Diameter (Imperial)

1.69 in

Overall Diameter (Metric)

4.3 cm

Overall Height (Imperial)

1.89 in

Overall Height (Metric)

4.8 cm

End Modification

Luer Lock

Micron Rating

0.8 μm

Flow Rate (Imperial)

0 gal/min

Flow Rate (Metric)

1 ml/min

Filter Type

Single Use

Net Weight (Metric)

10 g

Application

Anion exchange

Filter Technology

Anion exchange chromatography

Industries

Biopharmaceutical manufacturing

Product Series

Polisher ST

Category name

Chromatography Filters

Product ID

7100182144

Overall Diameter (Imperial)

17.72 in

Overall Diameter (Metric)

45 cm

Overall Height (Imperial)

8.74 in

Overall Height (Metric)

22.2 cm

End Modification

1 1/2 in Sanitary Connectors

Micron Rating

0.8 μm

Flow Rate (Imperial)

0.001 gal/min

Flow Rate (Metric)

16 l/min

Filter Type

Single Use

Net Weight (Metric)

12.7 kg

Application

Anion exchange

Filter Technology

Anion exchange chromatography

Industries

Biopharmaceutical manufacturing

Product Series

Polisher ST

Category name

Chromatography Filters

Product ID

7100179570

Overall Diameter (Imperial)

17.72 in

Overall Diameter (Metric)

45 cm

Overall Height (Imperial)

2.99 in

Overall Height (Metric)

7.6 cm

End Modification

1 1/2 in Sanitary Connectors

Micron Rating

0.8 μm

Flow Rate (Imperial)

0.506 gal/min

Flow Rate (Metric)

2.3 l/min

Filter Type

Single Use

Net Weight (Metric)

3.8 kg

Application

Anion exchange

Filter Technology

Anion exchange chromatography

Industries

Biopharmaceutical manufacturing

Product Series

Polisher ST

Category name

Chromatography Filters

Product ID

7100179560

Overall Diameter (Imperial)

9.49 in

Overall Diameter (Metric)

24.1 cm

Overall Height (Imperial)

5.98 in

Overall Height (Metric)

15.2 cm

End Modification

3/4 in Sanitary Connectors

Micron Rating

0.8 μm

Flow Rate (Imperial)

0.224 gal/min

Flow Rate (Metric)

1020 ml/min

Filter Type

Single Use

Net Weight (Metric)

1.8 kg

Application

Anion exchange

Filter Technology

Anion exchange chromatography

Industries

Biopharmaceutical manufacturing

Product Series

Polisher ST

Category name

Chromatography Filters

Product ID

7100179230

Overall Diameter (Imperial)

9.49 in

Overall Diameter (Metric)

24.1 cm

Overall Height (Imperial)

3.98 in

Overall Height (Metric)

10.1 cm

End Modification

3/4 in Sanitary Connectors

Micron Rating

0.8 μm

Flow Rate (Imperial)

0.037 gal/min

Flow Rate (Metric)

170 ml/min

Filter Type

Single Use

Net Weight (Metric)

1.1 kg

Application

Anion exchange

Filter Technology

Anion exchange chromatography

Industries

Biopharmaceutical manufacturing

Product Series

Polisher ST

Category name

Chromatography Filters

Product ID

7100179229

Overall Diameter (Imperial)

9.49 in

Overall Diameter (Metric)

24.1 cm

Overall Height (Imperial)

3.98 in

Overall Height (Metric)

10.1 cm

End Modification

3/4 in Sanitary Connectors

Micron Rating

0.8 μm

Flow Rate (Imperial)

0.075 gal/min

Flow Rate (Metric)

340 ml/min

Filter Type

Single Use

Net Weight (Metric)

1.2 kg

Application

Anion exchange

Filter Technology

Anion exchange chromatography

Industries

Biopharmaceutical manufacturing

Product Series

Polisher ST

Category name

Chromatography Filters

Product ID

7100179209

Overall Diameter (Imperial)

3.03 in

Overall Diameter (Metric)

7.7 cm

Overall Height (Imperial)

3.46 in

Overall Height (Metric)

8.8 cm

End Modification

3/4 in Sanitary Connectors

Micron Rating

0.8 μm

Flow Rate (Imperial)

0.005 gal/min

Flow Rate (Metric)

25 ml/min

Filter Type

Single Use

Net Weight (Metric)

78 g

Application

Anion exchange

Filter Technology

Anion exchange chromatography

Industries

Biopharmaceutical manufacturing

Product Series

Polisher ST

Category name

Chromatography Filters

Product ID

7100179207

Overall Diameter (Imperial)

3.03 in

Overall Diameter (Metric)

7.7 cm

Overall Height (Imperial)

1.77 in

Overall Height (Metric)

4.5 cm

End Modification

Luer Lock

Micron Rating

0.8 μm

Flow Rate (Imperial)

0.005 gal/min

Flow Rate (Metric)

25 ml/min

Filter Type

Single Use

Net Weight (Metric)

72 g

Application

Anion exchange

Filter Technology

Anion exchange chromatography

Industries

Biopharmaceutical manufacturing

Product Series

Polisher ST

Category name

Chromatography Filters

Product details

The Q-functional nonwoven provides reduction of turbidity (when present) and DNA. It also provides a portion of the product’s AEX capacity for HCP and virus reduction. Guanidinium functionalised membrane downstream of the functionalised nonwoven provides additional AEX polishing capacity. The novel guanidinium functionality of the downstream AEX polishing membrane mimics the amino acid, arginine, one of the three positively charged naturally occurring standard amino acids that make up proteins and is responsible for viral clearance and high salt tolerance.
  • Unaffected by process fluid turbidity up to 40 NTU.
  • The 3M™ Polisher ST is a single use multi-mechanism membrane adsorber which contains a Q-functional anion exchange non woven media and guanidinium functionalised membrane. This product removes residual turbidity, DNA and HCP and provides robust virus clearance for improved downstream/polishing purification.
  • Single-use technology as a cost-efficient option to increase biomass production by delivering high purity and yield in the downstream polishing unit operation in therapeutic recombinant protein process in biologically relevant operating conditions.
  • Replaces downstream AEX polishing column for reduction of HCP and virus in a salt tolerant (ST) manner as a single-use solution.
  • Provides DNA reduction in a salt tolerant (ST) manner compared with conventional Q-functional AEX resins.

Product specifications

Industries
Industries

Biopharmaceutical manufacturing

Net Weight (Metric)
Net Weight (Metric)

78 g, 10 g, 1.2 kg, 72 g, 15.5 g, 1.8 kg, 1.1 kg

Filter Technology
Filter Technology

Anion exchange chromatography

Micron Rating
Micron Rating

0.8 μm

OverallDiameterImperial
OverallDiameterImperial

9.49 in

Product Series
Product Series

Polisher ST

categoryName
categoryName

Chromatography Filters

Flow Rate (Imperial)
Flow Rate (Imperial)

0.075 gal/min, 0.005 gal/min, 0.001 gal/min, 0.224 gal/min, 0.037 gal/min

OverallHeightImperial
OverallHeightImperial

3.98 in

Overall Height (Imperial)
Overall Height (Imperial)

3.46 in, 1.89 in, 1.77 in, 2.32 in, 5.98 in, 2.99 in, 8.74 in

OverallHeightMetric
OverallHeightMetric

15.2 cm

FlowRateImperial
FlowRateImperial

0.005 gal/min, 0 gal/min, 0.506 gal/min

NetWeightMetric
NetWeightMetric

3.8 kg, 12.7 kg

End Modification
End Modification

3/4 in Sanitary Connectors, Luer Lock, 1 1/2 in Sanitary Connectors

Category name
Category name

Chromatography Filters

ProductSeries
ProductSeries

Polisher ST

Overall Height (Metric)
Overall Height (Metric)

8.8 cm, 4.8 cm, 10.1 cm, 4.5 cm, 5.9 cm, 7.6 cm, 22.2 cm

OverallDiameterMetric
OverallDiameterMetric

24.1 cm

Flow Rate (Metric)
Flow Rate (Metric)

25 ml/min, 1 ml/min, 340 ml/min, 4 ml/min, 1020 ml/min, 170 ml/min, 2.3 l/min, 16 l/min

EndModification
EndModification

Luer Lock

Global Catalog Number
Global Catalog Number

BC25, BC1, EMP301STX080R, BC4, BC1020, BC170, EMP710STX080R, EMP770STX080R

Overall Diameter (Imperial)
Overall Diameter (Imperial)

3.03 in, 1.69 in, 9.49 in, 17.72 in

GLBL_CAT_NBR
GLBL_CAT_NBR

BC340

Overall Diameter (Metric)
Overall Diameter (Metric)

7.7 cm, 4.3 cm, 24.1 cm, 45 cm

Filter Type
Filter Type

Single Use

FilterTechnology
FilterTechnology

Anion exchange chromatography

Application
Application

Anion exchange