3M™ Harvest RC Chromatographic Clarifier
Solventum’s Purification and Filtration Business is now a part of Thermo Fisher Scientific. Drinking Water Filtration remains with Solventum. For more information, please visit here.
About the product
3M™ Harvest RC is the next generation in harvest and clarification technology for high cell density cultures.
Product details
- Simplification of high cell density cell culture fluid clarification unit operations.
- Remove cells, cell debris and DNA (<500 ppb) from the harvested cell culture fluid.
- Optimised for PCV high density CHO cell culture (5-8% PCV)
- Replacement of primary, secondary and guard membrane clarification stages.
- Typical product recovery of 95+% (capsules)
- Synthetic chromatographic harvest media with chemically defined extractables.
- Predictable scaling from discovery to manufacturing.
- Lower total cost of manufacturing compared to centrifugation and depth filtration.
- Lower consumption of buffer and water compared to depth filtration.
- Capsules fit into laboratory to manufacturing scale workflows.
Suggested Applications
- Clarification for CHO harvest cell culture fluid
- Single-stage chromatographic clarification
- Single-stage chromatographic clarification
Legal
Always follow your user instruction manual.Product specifications
| Industries |
Industries
Biopharmaceutical manufacturing |
| Net Weight (Metric) |
Net Weight (Metric)
250 g, 75.8 g, 3.4 kg, 9.8 kg, 1.1 kg, 1.6 kg, 69.2 g, 10 g, 14.3 g |
| Filter Technology |
Filter Technology
Anion exchange chromatography |
| Micron Rating |
Micron Rating
0.2 μm |
| Product Series |
Product Series
Harvest RC |
| Flow Rate (Metric) |
Flow Rate (Metric)
4.2 ml/min, 0.38 l/min, 2.68 l/min, 57 ml/min, 170 ml/min, 0.53 ml/min |
| Flow Rate (Imperial) |
Flow Rate (Imperial)
0.001 gal/min, 0.1 gal/min, 0.594 gal/min, 0.013 gal/min, 0.037 gal/min, 0 gal/min |
| Overall Height (Imperial) |
Overall Height (Imperial)
0.63 in, 3.39 in, 2.24 in, 8.74 in, 4.09 in, 5.98 in, 2.09 in, 2.4 in, 3.46 in, 2.32 in |
| Overall Diameter (Imperial) |
Overall Diameter (Imperial)
43.7 in, 3.03 in, 17.8 in, 9.49 in, 1.14 in, 1.69 in |
| Overall Length (Imperial) |
Overall Length (Imperial)
5.04 in |
| Overall Width (Metric) |
Overall Width (Metric)
8.5 cm |
| Overall Length (Metric) |
Overall Length (Metric)
12.8 cm |
| Overall Diameter (Metric) |
Overall Diameter (Metric)
111 cm, 7.7 cm, 45.2 cm, 24.1 cm, 2.9 cm, 4.3 cm |
| End Modification |
End Modification
3/4 in Sanitary, 1 1/2 in Sanitary, Luer Lock |
| Filter Type |
Filter Type
Single Use |
| Category name |
Category name
Chromatography Filters |
| Overall Width (Imperial) |
Overall Width (Imperial)
3.35 in |
| Application |
Application
Harvest And Clarification |
| Overall Height (Metric) |
Overall Height (Metric)
16.1 mm, 8.6 cm, 5.7 cm, 22.2 cm, 10.4 cm, 15.2 cm, 5.3 cm, 6.1 cm, 8.8 cm, 5.9 cm |