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3M™ Polisher ST, BC170, EMP503STX080R, 1/Case

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3M™ Polisher ST, BC170, EMP503STX080R, 1/Case
3M Polisher ST Family photo
3M Polisher ST BC170 and BC340 side

Acerca del producto

The 3M™ Polisher ST is a fully encapsulated single-use anion exchange (AEX) product. It is intended to reduce host cell protein, viruses, and other negatively charged contaminants in a flow-through polishing chromatography mode in biopharmaceutical process streams. The 3M™ Polisher ST is a synthetic, hybrid purifier containing two complementary AEX-functional media: a quaternary ammonium (“Q”) functional nonwoven and a guanidinium-functional membrane.

  • FlowRateMetric : 170 ml/min
  • Industries : Fabricación de productos médicos biológicos
  • Tipo de Filtro : Un solo uso
  • Altura Total (métrica) : 10.1 cm
  • Capacidad En Micrones : 0.8 μm
  • Altura Total (Imperial) : 3.98 in
  • categoryName : Filtros de cromatografía
  • Serie de Producto : Pulidora ST
  • Aplicaciones : Intercambio aniónico
  • Diámetro total : 24.1 cm
  • Tecnología de Filtro : Cromatografía de intercambio de aniones
  • NetWeightMetric : 1.1 kg
  • Caudal de Flujo : 0.037 gal/min
  • Modificación Final : 3/4 in Sanitary Connectors
  • Diámetro total (Imperial) : 9.49 in

Detalles del producto

The Q-functional nonwoven provides reduction of turbidity (when present) and DNA. It also provides a portion of the product’s AEX capacity for HCP and virus reduction. Guanidinium functionalised membrane downstream of the functionalised nonwoven provides additional AEX polishing capacity. The novel guanidinium functionality of the downstream AEX polishing membrane mimics the amino acid, arginine, one of the three positively charged naturally occurring standard amino acids that make up proteins and is responsible for viral clearance and high salt tolerance.
  • Unaffected by process fluid turbidity up to 40 NTU.
  • The 3M™ Polisher ST is a single use multi-mechanism membrane adsorber which contains a Q-functional anion exchange non woven media and guanidinium functionalised membrane. This product removes residual turbidity, DNA and HCP and provides robust virus clearance for improved downstream/polishing purification.
  • Single-use technology as a cost-efficient option to increase biomass production by delivering high purity and yield in the downstream polishing unit operation in therapeutic recombinant protein process in biologically relevant operating conditions.
  • Replaces downstream AEX polishing column for reduction of HCP and virus in a salt tolerant (ST) manner as a single-use solution.
  • Provides DNA reduction in a salt tolerant (ST) manner compared with conventional Q-functional AEX resins.

Especificaciones del producto

FlowRateMetric
FlowRateMetric

170 ml/min

Industries
Industries

Fabricación de productos médicos biológicos

Tipo de Filtro
Tipo de Filtro

Un solo uso

Altura Total (métrica)
Altura Total (métrica)

10.1 cm

Capacidad En Micrones
Capacidad En Micrones

0.8 μm

Altura Total (Imperial)
Altura Total (Imperial)

3.98 in

categoryName
categoryName

Filtros de cromatografía

Serie de Producto
Serie de Producto

Pulidora ST

Aplicaciones
Aplicaciones

Intercambio aniónico

Diámetro total
Diámetro total

24.1 cm

Tecnología de Filtro
Tecnología de Filtro

Cromatografía de intercambio de aniones

NetWeightMetric
NetWeightMetric

1.1 kg

Caudal de Flujo
Caudal de Flujo

0.037 gal/min

Modificación Final
Modificación Final

3/4 in Sanitary Connectors

Diámetro total (Imperial)
Diámetro total (Imperial)

9.49 in

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