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3M™ Emphaze™ AEX Series Hybrid Purifier BV120R, EMP513AEX020R, 1/Case

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3M™ Emphaze™ AEX Series Hybrid Purifier BV120R, EMP513AEX020R, 1/Case

About the product

3M™ Emphaze AEX Hybrid Purifier is our single-use sterilisable and sanitisable. The all-synthetic purification media that contains a Q-functional anion exchange media and a fine particle and bioburden reduction membrane.

Details

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  • Industries : Biopharmaceutical manufacturing
  • Net Weight (Metric) : 1.1 kg
  • Filter Technology : Anion exchange chromatography
  • Micron Rating : 0.2 μm
  • OverallDiameterImperial : 8.5 in
  • Flow Rate (Metric) : 100 ml/min
  • OverallHeightImperial : 4.06 in
  • FlowRateImperial : 0.022 gal/min
  • Overall Diameter (Metric) : 21.6 cm
  • End Modification : 3/4 in Sanitary Connectors
  • Category name : Chromatography Filters
  • Filter Type : Single Use
  • ProductSeries : Emphaze AEX
  • Trademark2 : Emphaze™
  • Application : Harvest And Clarification
  • Overall Height (Metric) : 10.3 cm

Product details

Remove impurities in biopharmaceutical process streams such as DNA, host cell proteins (HCP) and viruses with our all-synthetic, single use 3M™ Emphaze AEX Hybrid Purifier. The composite purification media is comprised of three primary components: anion exchange nonwoven, microporous membrane, and membrane support. The anion exchange media is composed of four layers of polypropylene nonwoven with a covalently attached quaternary ammonium functional polymer. The bioburden reduction membrane is a highly asymmetric polyamide membrane which has nine zones of decreasing pore size, spanning approximately a 20 X range, and terminating with a 0.2 μm rated qualifying layer. This is followed by a polypropylene nonwoven used as a support layer in the capsule. Capsules There are two primary capsule configurations for the Emphaze AEX Hybrid Purifier, Laboratory and Scale-up capsules: - The Laboratory capsule (BV8) has an 8ml bed volume - The Scale-up capsules are constructed from a lenticular media cell design having bed volumes of 120 mls and 360 mls (BV 120 and BV 360 respectively) - The Production capsules are scaled to meet your manufacturing requirements and utilise manifolds in a holder for ease of use A full support package is available for 3M Emphaze AEX Hybrid Purifiers. This package includes Installation and Operation Guides, a Certificate of Quality and a Regulatory Support File.
  • All-synthetic, highly functionalised media (contains no naturally-derived materials)
  • Asymmetric membrane ending with a 0.2 µm bioburden reduction zone
  • Excellent mAb recovery, often equal to or greater than 95%
  • Substantial turbidity, DNA, HCP and bioburden reduction
  • Reduced surface area requirement of the downstream sterilising grade membrane
  • May offer differentiated protection to the protein A column for enhanced contaminant clearance performance
  • All product components comply with United States Pharmacopeia (USP) <88> Class VI 70°C Biological Reactivity Tests, in vivo
  • Autoclavable

Suggested Applications

  • Use for the clarification of mammalian cell cultures and to optimise downstream processes for monoclonal antibodies (mAbs)

Product specifications

Industries
Industries

Biopharmaceutical manufacturing

Net Weight (Metric)
Net Weight (Metric)

1.1 kg

Filter Technology
Filter Technology

Anion exchange chromatography

Micron Rating
Micron Rating

0.2 μm

OverallDiameterImperial
OverallDiameterImperial

8.5 in

Flow Rate (Metric)
Flow Rate (Metric)

100 ml/min

OverallHeightImperial
OverallHeightImperial

4.06 in

FlowRateImperial
FlowRateImperial

0.022 gal/min

Overall Diameter (Metric)
Overall Diameter (Metric)

21.6 cm

End Modification
End Modification

3/4 in Sanitary Connectors

Category name
Category name

Chromatography Filters

Filter Type
Filter Type

Single Use

ProductSeries
ProductSeries

Emphaze AEX

Trademark2
Trademark2

Emphaze™

Application
Application

Harvest And Clarification

Overall Height (Metric)
Overall Height (Metric)

10.3 cm