3M™ Emphaze™ AEX Hybrid Purifier

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About the product

3M™ Emphaze AEX Hybrid Purifier is our single-use sterilisable and sanitisable. The all-synthetic purification media that contains a Q-functional anion exchange media and a fine particle and bioburden reduction membrane.

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Product name	Product ID	Overall Diameter (Imperial)	OverallDiameterMetric	Overall Height (Imperial)	Overall Height (Metric)	End Modification	Micron Rating	Flow Rate (Imperial)	Flow Rate (Metric)	Filter Type	Net Weight (Metric)	Application	Filter Technology	Industries	Product Series	Brand	Category name
3M™ Emphaze™ AEX Series Hybrid Purifier BV0.3R, EMP101AEX020R, 4/Case	Product ID 7100179206	Overall Diameter (Imperial) 1.69 in	OverallDiameterMetric 4.3 cm	Overall Height (Imperial) 1.89 in	Overall Height (Metric) 4.8 cm	End Modification Luer Lock	Micron Rating 0.2 μm	Flow Rate (Imperial) 0 gal/min	Flow Rate (Metric) 0.4 ml/min	Filter Type Single Use	Net Weight (Metric) 9 g	Application Harvest And Clarification	Filter Technology Anion exchange chromatography	Industries Biopharmaceutical manufacturing	Product Series Emphaze AEX	Brand Emphaze™	Category name Chromatography Filters
3M™ Emphaze™ AEX Series Hybrid Purifier BV1, EMP201AEX020R, 4/Case	Product ID 7100174193	Overall Diameter (Imperial) 1.69 in	OverallDiameterMetric 4.3 cm	Overall Height (Imperial) 2.32 in	Overall Height (Metric) 5.9 cm	End Modification Luer Lock	Micron Rating 0.2 μm	Flow Rate (Imperial) 0 gal/min	Flow Rate (Metric) 1.4 ml/min	Filter Type Single Use	Net Weight (Metric) 14.5 g	Application Harvest And Clarification	Filter Technology Anion exchange chromatography	Industries Biopharmaceutical manufacturing	Product Series Emphaze AEX	Brand Emphaze™	Category name Chromatography Filters
3M™ Emphaze™ AEX Series Hybrid Purifier BV120R, EMP513AEX020R, 1/Case	Product ID 7100166976	Overall Diameter (Imperial) 8.5 in	OverallDiameterMetric 21.6 cm	Overall Height (Imperial) 4.06 in	Overall Height (Metric) 10.3 cm	End Modification 3/4 in Sanitary Connectors	Micron Rating 0.2 μm	Flow Rate (Imperial) 0.022 gal/min	Flow Rate (Metric) 100 ml/min	Filter Type Single Use	Net Weight (Metric) 1.1 kg	Application Harvest And Clarification	Filter Technology Anion exchange chromatography	Industries Biopharmaceutical manufacturing	Product Series Emphaze AEX	Brand Emphaze™	Category name Chromatography Filters
3M™ Emphaze™ AEX Series Hybrid Purifier BV5600R, EMP770AEX020R, 16 in,1/Case	Product ID 7100158437	Overall Diameter (Imperial) 17.8 in	OverallDiameterMetric 45.2 cm	Overall Height (Imperial) 7.99 in	Overall Height (Metric) 20.3 cm	End Modification 1 1/2 in Sanitary Connectors	Micron Rating 0.2 μm	Flow Rate (Imperial) 1.034 gal/min	Flow Rate (Metric) 4700 ml/min	Filter Type Single Use	Net Weight (Metric) 9.5 kg	Application Harvest And Clarification	Filter Technology Anion exchange chromatography	Industries Biopharmaceutical manufacturing	Product Series Emphaze AEX	Brand Emphaze™	Category name Chromatography Filters
3M™ Emphaze™ AEX Series Hybrid Purifier BV800, EMP710AEX020R, 16 in,1/Case	Product ID 7100158436	Overall Diameter (Imperial) 17.8 in	OverallDiameterMetric 45.2 cm	Overall Height (Imperial) 2.24 in	Overall Height (Metric) 5.7 cm	End Modification 1 1/2 in Sanitary Connectors	Micron Rating 0.2 μm	Flow Rate (Imperial) 0.15 gal/min	Flow Rate (Metric) 680 ml/min	Filter Type Single Use	Net Weight (Metric) 3.4 kg	Application Harvest And Clarification	Filter Technology Anion exchange chromatography	Industries Biopharmaceutical manufacturing	Product Series Emphaze AEX	Brand Emphaze™	Category name Chromatography Filters
3M™ Emphaze™ AEX Series Hybrid Purifier BV360, EMP533AEX020R, 1/CS	Product ID 7100158435	Overall Diameter (Imperial) 8.5 in	OverallDiameterMetric 21.6 cm	Overall Height (Imperial) 5.98 in	Overall Height (Metric) 15.2 cm	End Modification 3/4 in Sanitary Connectors	Micron Rating 0.2 μm	Flow Rate (Imperial) 0.066 gal/min	Flow Rate (Metric) 300 ml/min	Filter Type Single Use	Net Weight (Metric) 1.6 kg	Application Harvest And Clarification	Filter Technology Anion exchange chromatography	Industries Biopharmaceutical manufacturing	Product Series Emphaze AEX	Brand Emphaze™	Category name Chromatography Filters
3M™ Emphaze™ AEX Series Hybrid Purifier BV8, EMP303AEX020R, Sanitary,2/Case	Product ID 7100158434	Overall Diameter (Imperial) 3.03 in	OverallDiameterMetric 7.7 cm	Overall Height (Imperial) 3.46 in	Overall Height (Metric) 8.8 cm	End Modification 3/4 in Sanitary Connectors	Micron Rating 0.2 μm	Flow Rate (Imperial) 0.002 gal/min	Flow Rate (Metric) 8 ml/min	Filter Type Single Use	Net Weight (Metric) 77 g	Application Harvest And Clarification	Filter Technology Anion exchange chromatography	Industries Biopharmaceutical manufacturing	Product Series Emphaze AEX	Brand Emphaze™	Category name Chromatography Filters
3M™ Emphaze™ AEX Series Hybrid Purifier BV8R, EMP301AEX020R, Luer,2/Case	Product ID 7100158433	Overall Diameter (Imperial) 3.03 in	OverallDiameterMetric 7.7 cm	Overall Height (Imperial) 1.77 in	Overall Height (Metric) 4.5 cm	End Modification Luer Lock	Micron Rating 0.2 μm	Flow Rate (Imperial) 0.002 gal/min	Flow Rate (Metric) 8 ml/min	Filter Type Single Use	Net Weight (Metric) 71 g	Application Harvest And Clarification	Filter Technology Anion exchange chromatography	Industries Biopharmaceutical manufacturing	Product Series Emphaze AEX	Brand Emphaze™	Category name Chromatography Filters
3M™ Emphaze™ AEX Series Hybrid Purifier BV60, EMP503AEX020R, 1/Case	Product ID 7100158416	Overall Diameter (Imperial) 8.5 in	OverallDiameterMetric 21.6 cm	Overall Height (Imperial) 4.06 in	Overall Height (Metric) 10.3 cm	End Modification 3/4 in Sanitary Connectors	Micron Rating 0.2 μm	Flow Rate (Imperial) 0.011 gal/min	Flow Rate (Metric) 50 ml/min	Filter Type Single Use	Net Weight (Metric) 1 kg	Application Harvest And Clarification	Filter Technology Anion exchange chromatography	Industries Biopharmaceutical manufacturing	Product Series Emphaze AEX	Brand Emphaze™	Category name Chromatography Filters

Product details

Remove impurities in biopharmaceutical process streams such as DNA, host cell proteins (HCP) and viruses with our all-synthetic, single use 3M™ Emphaze AEX Hybrid Purifier. The composite purification media is comprised of three primary components: anion exchange nonwoven, microporous membrane, and membrane support. The anion exchange media is composed of four layers of polypropylene nonwoven with a covalently attached quaternary ammonium functional polymer. The bioburden reduction membrane is a highly asymmetric polyamide membrane which has nine zones of decreasing pore size, spanning approximately a 20 X range, and terminating with a 0.2 μm rated qualifying layer. This is followed by a polypropylene nonwoven used as a support layer in the capsule. Capsules There are two primary capsule configurations for the Emphaze AEX Hybrid Purifier, Laboratory and Scale-up capsules: - The Laboratory capsule (BV8) has an 8ml bed volume - The Scale-up capsules are constructed from a lenticular media cell design having bed volumes of 120 mls and 360 mls (BV 120 and BV 360 respectively) - The Production capsules are scaled to meet your manufacturing requirements and utilise manifolds in a holder for ease of use A full support package is available for 3M Emphaze AEX Hybrid Purifiers. This package includes Installation and Operation Guides, a Certificate of Quality and a Regulatory Support File.

All-synthetic, highly functionalised media (contains no naturally-derived materials)
Asymmetric membrane ending with a 0.2 µm bioburden reduction zone
Excellent mAb recovery, often equal to or greater than 95%
Substantial turbidity, DNA, HCP and bioburden reduction
Reduced surface area requirement of the downstream sterilising grade membrane
May offer differentiated protection to the protein A column for enhanced contaminant clearance performance
All product components comply with United States Pharmacopeia (USP) <88> Class VI 70°C Biological Reactivity Tests, in vivo
Autoclavable

Suggested Applications

Use for the clarification of mammalian cell cultures and to optimise downstream processes for monoclonal antibodies (mAbs)

Product specifications

Industries	Industries Biopharmaceutical manufacturing
Net Weight (Metric)	Net Weight (Metric) 1.1 kg, 14.5 g, 1.6 kg, 9 g, 71 g, 77 g
Filter Technology	Filter Technology Anion exchange chromatography
Micron Rating	Micron Rating 0.2 μm
OverallDiameterImperial	OverallDiameterImperial 17.8 in, 8.5 in, 1.69 in
Product Series	Product Series Emphaze AEX
categoryName	categoryName Chromatography Filters
Flow Rate (Imperial)	Flow Rate (Imperial) 0.022 gal/min, 1.034 gal/min, 0.011 gal/min, 0.066 gal/min, 0.15 gal/min, 0 gal/min, 0.002 gal/min
OverallHeightImperial	OverallHeightImperial 7.99 in
Overall Height (Imperial)	Overall Height (Imperial) 4.06 in, 2.32 in, 5.98 in, 2.24 in, 1.89 in, 1.77 in, 3.46 in
OverallHeightMetric	OverallHeightMetric 4.8 cm
FlowRateImperial	FlowRateImperial 0 gal/min, 0.002 gal/min
NetWeightMetric	NetWeightMetric 9.5 kg, 3.4 kg
End Modification	End Modification 3/4 in Sanitary Connectors, 1 1/2 in Sanitary Connectors, Luer Lock
Category name	Category name Chromatography Filters
ProductSeries	ProductSeries Emphaze AEX
Trademark2	Trademark2 Emphaze™
Overall Height (Metric)	Overall Height (Metric) 10.3 cm, 5.9 cm, 20.3 cm, 15.2 cm, 5.7 cm, 4.5 cm, 8.8 cm
FlowRateMetric	FlowRateMetric 100 ml/min, 4700 ml/min
MicronRating	MicronRating 0.2 μm
OverallDiameterMetric	OverallDiameterMetric 21.6 cm, 7.7 cm
Flow Rate (Metric)	Flow Rate (Metric) 1.4 ml/min, 50 ml/min, 300 ml/min, 680 ml/min, 0.4 ml/min, 8 ml/min
EndModification	EndModification Luer Lock
Brand	Brand Emphaze™
FilterType	FilterType Single Use
Overall Diameter (Imperial)	Overall Diameter (Imperial) 8.5 in, 1.69 in, 17.8 in, 3.03 in
Overall Diameter (Metric)	Overall Diameter (Metric) 21.6 cm, 4.3 cm, 45.2 cm, 7.7 cm
Filter Type	Filter Type Single Use
FilterTechnology	FilterTechnology Anion exchange chromatography
Application	Application Harvest And Clarification

3M™ Emphaze™ AEX Hybrid Purifier

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