3M™ Polisher ST
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Over het product
The 3M™ Polisher ST is a fully encapsulated single-use anion exchange (AEX) product. It is intended to reduce host cell protein, viruses, and other negatively charged contaminants in a flow-through polishing chromatography mode in biopharmaceutical process streams. The 3M™ Polisher ST is a synthetic, hybrid purifier containing two complementary AEX-functional media: a quaternary ammonium (“Q”) functional nonwoven and a guanidinium-functional membrane.
Productdetails
- Unaffected by process fluid turbidity up to 40 NTU.
- The 3M™ Polisher ST is a single use multi-mechanism membrane adsorber which contains a Q-functional anion exchange non woven media and guanidinium functionalised membrane. This product removes residual turbidity, DNA and HCP and provides robust virus clearance for improved downstream/polishing purification.
- Single-use technology as a cost-efficient option to increase biomass production by delivering high purity and yield in the downstream polishing unit operation in therapeutic recombinant protein process in biologically relevant operating conditions.
- Replaces downstream AEX polishing column for reduction of HCP and virus in a salt tolerant (ST) manner as a single-use solution.
- Provides DNA reduction in a salt tolerant (ST) manner compared with conventional Q-functional AEX resins.
Productspecificaties
| Eindaanpassing |
Eindaanpassing
3/4 in Sanitary Connectors, Luer Lock, 1 1/2 in Sanitary Connectors |
| Categorienaam |
Categorienaam
Chromatografiefilters |
| Totale hoogte (imperiaal) |
Totale hoogte (imperiaal)
3.46 in, 1.89 in, 3.98 in, 1.77 in, 2.32 in, 5.98 in, 2.99 in, 8.74 in |
| Toepassing |
Toepassing
Anion exchange |
| Micronage |
Micronage
0.8 μm |
| Totale hoogte (metrisch) |
Totale hoogte (metrisch)
8.8 cm, 4.8 cm, 10.1 cm, 4.5 cm, 5.9 cm, 15.2 cm, 7.6 cm, 22.2 cm |
| Totale diameter (metrisch) |
Totale diameter (metrisch)
7.7 cm, 4.3 cm, 24.1 cm, 45 cm |
| Debiet (metrisch) |
Debiet (metrisch)
25 ml/min, 1 ml/min, 340 ml/min, 4 ml/min, 1020 ml/min, 170 ml/min, 2.3 l/min, 16 l/min |
| Global Catalog Number |
Global Catalog Number
BC25, BC1, BC340, EMP301STX080R, BC4, BC1020, BC170, EMP710STX080R, EMP770STX080R |
| Debiet |
Debiet
0.005 gal/min, 0 gal/min, 0.075 gal/min, 0.001 gal/min, 0.224 gal/min, 0.037 gal/min, 0.506 gal/min |
| Sectoren |
Sectoren
Biofarmaceutische productie |
| Totale diameter (Brits) |
Totale diameter (Brits)
3.03 in, 1.69 in, 9.49 in, 17.72 in |
| Productserie |
Productserie
Polisher ST |
| Filtertype |
Filtertype
Eenmalig gebruik |
| Filtertechnologie |
Filtertechnologie
Anion exchange-chromatografie |
| Nettogewicht (metrisch) |
Nettogewicht (metrisch)
78 g, 10 g, 1.2 kg, 72 g, 15.5 g, 1.8 kg, 1.1 kg, 3.8 kg, 12.7 kg |