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3M™ Emphaze™ AEX Series Hybrid Purifier BV0.3R, EMP101AEX020R, 4/Case

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3M™ Emphaze™ AEX Series Hybrid Purifier BV0.3R, EMP101AEX020R, 4/Case
3M™ Emphaze™ AEX Hybrid Purifier Family

Om produktet

3M™ Emphaze AEX Hybrid Purifier is our single-use sterilisable and sanitisable. The all-synthetic purification media that contains a Q-functional anion exchange media and a fine particle and bioburden reduction membrane.

  • FlowRateMetric : 0.4 ml/min
  • Afslut ændring : Luer Lock
  • OverallDiameterMetric : 4.3 cm
  • Samlet højde (metrisk standard) : 4.8 cm
  • Flowhastighed (britisk mål) : 0 gal/min
  • OverallDiameterImperial : 1.69 in
  • categoryName : Kromatografifiltre
  • OverallHeightImperial : 1.89 in
  • Global Catalog Number : EMP101AEX020R
  • FilterType : Engangsbrug
  • NetWeightMetric : 9 g
  • Brancher : Biofarmaceutisk produktion
  • Mikron-vurdering : 0.2 μm
  • Trademark2 : Emphaze™
  • Produktserie : Emphaze AEX
  • FilterTechnology : Anion-udvekslingskromatografi
  • Application : Høst og klaring

Produktdetaljer

Remove impurities in biopharmaceutical process streams such as DNA, host cell proteins (HCP) and viruses with our all-synthetic, single use 3M™ Emphaze AEX Hybrid Purifier. The composite purification media is comprised of three primary components: anion exchange nonwoven, microporous membrane, and membrane support. The anion exchange media is composed of four layers of polypropylene nonwoven with a covalently attached quaternary ammonium functional polymer. The bioburden reduction membrane is a highly asymmetric polyamide membrane which has nine zones of decreasing pore size, spanning approximately a 20 X range, and terminating with a 0.2 μm rated qualifying layer. This is followed by a polypropylene nonwoven used as a support layer in the capsule. Capsules There are two primary capsule configurations for the Emphaze AEX Hybrid Purifier, Laboratory and Scale-up capsules: - The Laboratory capsule (BV8) has an 8ml bed volume - The Scale-up capsules are constructed from a lenticular media cell design having bed volumes of 120 mls and 360 mls (BV 120 and BV 360 respectively) - The Production capsules are scaled to meet your manufacturing requirements and utilise manifolds in a holder for ease of use A full support package is available for 3M Emphaze AEX Hybrid Purifiers. This package includes Installation and Operation Guides, a Certificate of Quality and a Regulatory Support File.
  • All-synthetic, highly functionalised media (contains no naturally-derived materials)
  • Asymmetric membrane ending with a 0.2 µm bioburden reduction zone
  • Excellent mAb recovery, often equal to or greater than 95%
  • Substantial turbidity, DNA, HCP and bioburden reduction
  • Reduced surface area requirement of the downstream sterilising grade membrane
  • May offer differentiated protection to the protein A column for enhanced contaminant clearance performance
  • All product components comply with United States Pharmacopeia (USP) <88> Class VI 70°C Biological Reactivity Tests, in vivo
  • Autoclavable

Foreslåede anvendelser

  • Use for the clarification of mammalian cell cultures and to optimise downstream processes for monoclonal antibodies (mAbs)

Produktspecifikationer

FlowRateMetric
FlowRateMetric

0.4 ml/min

Afslut ændring
Afslut ændring

Luer Lock

OverallDiameterMetric
OverallDiameterMetric

4.3 cm

Samlet højde (metrisk standard)
Samlet højde (metrisk standard)

4.8 cm

Flowhastighed (britisk mål)
Flowhastighed (britisk mål)

0 gal/min

OverallDiameterImperial
OverallDiameterImperial

1.69 in

categoryName
categoryName

Kromatografifiltre

OverallHeightImperial
OverallHeightImperial

1.89 in

Global Catalog Number
Global Catalog Number

EMP101AEX020R

FilterType
FilterType

Engangsbrug

NetWeightMetric
NetWeightMetric

9 g

Brancher
Brancher

Biofarmaceutisk produktion

Mikron-vurdering
Mikron-vurdering

0.2 μm

Trademark2
Trademark2

Emphaze™

Produktserie
Produktserie

Emphaze AEX

FilterTechnology
FilterTechnology

Anion-udvekslingskromatografi

Application
Application

Høst og klaring