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3M™ Polisher ST, BC1, 4/Case

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3M™ Polisher ST, BC1, 4/Case
3M Polisher ST Family photo

Informazioni sul prodotto

The 3M™ Polisher ST is a fully encapsulated single-use anion exchange (AEX) product. It is intended to reduce host cell protein, viruses, and other negatively charged contaminants in a flow-through polishing chromatography mode in biopharmaceutical process streams. The 3M™ Polisher ST is a synthetic, hybrid purifier containing two complementary AEX-functional media: a quaternary ammonium (“Q”) functional nonwoven and a guanidinium-functional membrane.

  • Grado (di filtrazione) nominale : 0.8 μm
  • Fine modifica : Luer Lock
  • Portata (misure metriche) : 1 ml/min
  • Settori : Produzione biofarmaceutica
  • OverallDiameterMetric : 4.3 cm
  • Nome categoria : Filtri cromatografici
  • Diametro (unità misura Imperiale anglosassone) : 1.69 in
  • OverallHeightImperial : 1.89 in
  • FilterType : Monouso
  • FlowRateImperial : 0 gal/min
  • Altezza complessiva (misure metriche) : 4.8 cm
  • NetWeightMetric : 10 g
  • GLBL_CAT_NBR : BC1
  • ProductSeries : Lucidatrice ST
  • FilterTechnology : Cromatografia a scambio anionico
  • Application : Scambio anionico

Dettagli del prodotto

The Q-functional nonwoven provides reduction of turbidity (when present) and DNA. It also provides a portion of the product’s AEX capacity for HCP and virus reduction. Guanidinium functionalised membrane downstream of the functionalised nonwoven provides additional AEX polishing capacity. The novel guanidinium functionality of the downstream AEX polishing membrane mimics the amino acid, arginine, one of the three positively charged naturally occurring standard amino acids that make up proteins and is responsible for viral clearance and high salt tolerance.
  • Unaffected by process fluid turbidity up to 40 NTU.
  • The 3M™ Polisher ST is a single use multi-mechanism membrane adsorber which contains a Q-functional anion exchange non woven media and guanidinium functionalised membrane. This product removes residual turbidity, DNA and HCP and provides robust virus clearance for improved downstream/polishing purification.
  • Single-use technology as a cost-efficient option to increase biomass production by delivering high purity and yield in the downstream polishing unit operation in therapeutic recombinant protein process in biologically relevant operating conditions.
  • Replaces downstream AEX polishing column for reduction of HCP and virus in a salt tolerant (ST) manner as a single-use solution.
  • Provides DNA reduction in a salt tolerant (ST) manner compared with conventional Q-functional AEX resins.

Specifiche del prodotto

Grado (di filtrazione) nominale
Grado (di filtrazione) nominale

0.8 μm

Fine modifica
Fine modifica

Luer Lock

Portata (misure metriche)
Portata (misure metriche)

1 ml/min

Settori
Settori

Produzione biofarmaceutica

OverallDiameterMetric
OverallDiameterMetric

4.3 cm

Nome categoria
Nome categoria

Filtri cromatografici

Diametro (unità misura Imperiale anglosassone)
Diametro (unità misura Imperiale anglosassone)

1.69 in

OverallHeightImperial
OverallHeightImperial

1.89 in

FilterType
FilterType

Monouso

FlowRateImperial
FlowRateImperial

0 gal/min

Altezza complessiva (misure metriche)
Altezza complessiva (misure metriche)

4.8 cm

NetWeightMetric
NetWeightMetric

10 g

GLBL_CAT_NBR
GLBL_CAT_NBR

BC1

ProductSeries
ProductSeries

Lucidatrice ST

FilterTechnology
FilterTechnology

Cromatografia a scambio anionico

Application
Application

Scambio anionico

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