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3M™ Emphaze™ AEX Series Hybrid Purifier BV120R, EMP513AEX020R, 1/Case

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3M™ Emphaze™ AEX Series Hybrid Purifier BV120R, EMP513AEX020R, 1/Case

O produkcie

3M™ Emphaze AEX Hybrid Purifier is our single-use sterilisable and sanitisable. The all-synthetic purification media that contains a Q-functional anion exchange media and a fine particle and bioburden reduction membrane.

  • FlowRateMetric : 100 ml/min
  • Industries : Produkcja biofarmaceutyczna
  • MicronRating : 0.2 μm
  • OverallDiameterMetric : 21.6 cm
  • OverallDiameterImperial : 8.5 in
  • EndModification : 3/4 in Sanitary Connectors
  • categoryName : Filtry chromatograficzne
  • OverallHeightImperial : 4.06 in
  • Global Catalog Number : EMP513AEX020R
  • Rodzaj filtra : Jednorazowego użytku
  • Zastosowanie : Pobieranie i klarowanie
  • Wysokość całkowita (jednostki metryczne) : 10.3 cm
  • Przepływ (jednostki imperialne) : 0.022 gal/min
  • Technologia filtra : Chromatografia z wymianą anionów
  • NetWeightMetric : 1.1 kg
  • Linia produktów : Emphaze AEX
  • Marka : Emphaze™

Szczegóły produktu

Remove impurities in biopharmaceutical process streams such as DNA, host cell proteins (HCP) and viruses with our all-synthetic, single use 3M™ Emphaze AEX Hybrid Purifier. The composite purification media is comprised of three primary components: anion exchange nonwoven, microporous membrane, and membrane support. The anion exchange media is composed of four layers of polypropylene nonwoven with a covalently attached quaternary ammonium functional polymer. The bioburden reduction membrane is a highly asymmetric polyamide membrane which has nine zones of decreasing pore size, spanning approximately a 20 X range, and terminating with a 0.2 μm rated qualifying layer. This is followed by a polypropylene nonwoven used as a support layer in the capsule. Capsules There are two primary capsule configurations for the Emphaze AEX Hybrid Purifier, Laboratory and Scale-up capsules: - The Laboratory capsule (BV8) has an 8ml bed volume - The Scale-up capsules are constructed from a lenticular media cell design having bed volumes of 120 mls and 360 mls (BV 120 and BV 360 respectively) - The Production capsules are scaled to meet your manufacturing requirements and utilise manifolds in a holder for ease of use A full support package is available for 3M Emphaze AEX Hybrid Purifiers. This package includes Installation and Operation Guides, a Certificate of Quality and a Regulatory Support File.
  • All-synthetic, highly functionalised media (contains no naturally-derived materials)
  • Asymmetric membrane ending with a 0.2 µm bioburden reduction zone
  • Excellent mAb recovery, often equal to or greater than 95%
  • Substantial turbidity, DNA, HCP and bioburden reduction
  • Reduced surface area requirement of the downstream sterilising grade membrane
  • May offer differentiated protection to the protein A column for enhanced contaminant clearance performance
  • All product components comply with United States Pharmacopeia (USP) <88> Class VI 70°C Biological Reactivity Tests, in vivo
  • Autoclavable

Sugerowane zastosowania

  • Use for the clarification of mammalian cell cultures and to optimise downstream processes for monoclonal antibodies (mAbs)

Specyfikacje produktu

FlowRateMetric
FlowRateMetric

100 ml/min

Industries
Industries

Produkcja biofarmaceutyczna

MicronRating
MicronRating

0.2 μm

OverallDiameterMetric
OverallDiameterMetric

21.6 cm

OverallDiameterImperial
OverallDiameterImperial

8.5 in

EndModification
EndModification

3/4 in Sanitary Connectors

categoryName
categoryName

Filtry chromatograficzne

OverallHeightImperial
OverallHeightImperial

4.06 in

Global Catalog Number
Global Catalog Number

EMP513AEX020R

Rodzaj filtra
Rodzaj filtra

Jednorazowego użytku

Zastosowanie
Zastosowanie

Pobieranie i klarowanie

Wysokość całkowita (jednostki metryczne)
Wysokość całkowita (jednostki metryczne)

10.3 cm

Przepływ (jednostki imperialne)
Przepływ (jednostki imperialne)

0.022 gal/min

Technologia filtra
Technologia filtra

Chromatografia z wymianą anionów

NetWeightMetric
NetWeightMetric

1.1 kg

Linia produktów
Linia produktów

Emphaze AEX

Marka
Marka

Emphaze™