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  1. 3M™ Polisher ST

3M™ Polisher ST, BC16000, EMP770STX080R,16 in, 7-Cell, 1/Case

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3M™ Polisher ST, BC16000, EMP770STX080R,16 in, 7-Cell, 1/Case
3M Polisher ST Family photo

Om produktet

The 3M™ Polisher ST is a fully encapsulated single-use anion exchange (AEX) product. It is intended to reduce host cell protein, viruses, and other negatively charged contaminants in a flow-through polishing chromatography mode in biopharmaceutical process streams. The 3M™ Polisher ST is a synthetic, hybrid purifier containing two complementary AEX-functional media: a quaternary ammonium (“Q”) functional nonwoven and a guanidinium-functional membrane.

  • Industries : Biofarmasøytisk produksjon
  • Mirkonrate : 0.8 μm
  • OverallDiameterMetric : 45 cm
  • Avslutt endring : 1 1/2 in Sanitary Connectors
  • Flowfrekvens (Imperial) : 0.001 gal/min
  • Filterteknologi : Anionbytterkromatografi
  • Flowfrekvens (Metrisk) : 4 ml/min
  • categoryName : Kromatografiske filtre
  • Nettovekt (metrisk) : 12.7 kg
  • FilterType : Engangsbruk
  • Total høyde (Metrisk) : 22.2 cm
  • Total diameter (Imperial) : 17.72 in
  • Produktserier : Poleringsmaskin ST
  • Application : Anionebytte
  • Total høyde (Imperial) : 8.74 in

Produktdetaljer

The Q-functional nonwoven provides reduction of turbidity (when present) and DNA. It also provides a portion of the product’s AEX capacity for HCP and virus reduction. Guanidinium functionalised membrane downstream of the functionalised nonwoven provides additional AEX polishing capacity. The novel guanidinium functionality of the downstream AEX polishing membrane mimics the amino acid, arginine, one of the three positively charged naturally occurring standard amino acids that make up proteins and is responsible for viral clearance and high salt tolerance.
  • Unaffected by process fluid turbidity up to 40 NTU.
  • The 3M™ Polisher ST is a single use multi-mechanism membrane adsorber which contains a Q-functional anion exchange non woven media and guanidinium functionalised membrane. This product removes residual turbidity, DNA and HCP and provides robust virus clearance for improved downstream/polishing purification.
  • Single-use technology as a cost-efficient option to increase biomass production by delivering high purity and yield in the downstream polishing unit operation in therapeutic recombinant protein process in biologically relevant operating conditions.
  • Replaces downstream AEX polishing column for reduction of HCP and virus in a salt tolerant (ST) manner as a single-use solution.
  • Provides DNA reduction in a salt tolerant (ST) manner compared with conventional Q-functional AEX resins.

Produktspecifikasjoner

Industries
Industries

Biofarmasøytisk produksjon

Mirkonrate
Mirkonrate

0.8 μm

OverallDiameterMetric
OverallDiameterMetric

45 cm

Avslutt endring
Avslutt endring

1 1/2 in Sanitary Connectors

Flowfrekvens (Imperial)
Flowfrekvens (Imperial)

0.001 gal/min

Filterteknologi
Filterteknologi

Anionbytterkromatografi

Flowfrekvens (Metrisk)
Flowfrekvens (Metrisk)

4 ml/min

categoryName
categoryName

Kromatografiske filtre

Nettovekt (metrisk)
Nettovekt (metrisk)

12.7 kg

FilterType
FilterType

Engangsbruk

Total høyde (Metrisk)
Total høyde (Metrisk)

22.2 cm

Total diameter (Imperial)
Total diameter (Imperial)

17.72 in

Produktserier
Produktserier

Poleringsmaskin ST

Application
Application

Anionebytte

Total høyde (Imperial)
Total høyde (Imperial)

8.74 in