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  1. 3M™ Polisher ST

3M™ Polisher ST, BC1020, 1/Case

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3M™ Polisher ST, BC1020, 1/Case
3M Polisher ST Family photo

Informazioni sul prodotto

The 3M™ Polisher ST is a fully encapsulated single-use anion exchange (AEX) product. It is intended to reduce host cell protein, viruses, and other negatively charged contaminants in a flow-through polishing chromatography mode in biopharmaceutical process streams. The 3M™ Polisher ST is a synthetic, hybrid purifier containing two complementary AEX-functional media: a quaternary ammonium (“Q”) functional nonwoven and a guanidinium-functional membrane.

  • MicronRating : 0.8 μm
  • Fine modifica : 3/4 in Sanitary Connectors
  • Portata (misure metriche) : 1020 ml/min
  • Settori : Produzione biofarmaceutica
  • Applicazioni : Scambio anionico
  • Nome categoria : Filtri cromatografici
  • Serie prodotto : Lucidatrice ST
  • OverallDiameterImperial : 9.49 in
  • Portata (misure imperiali) : 0.224 gal/min
  • Tipo di filtro : Monouso
  • OverallHeightImperial : 5.98 in
  • Altezza complessiva (misure metriche) : 15.2 cm
  • NetWeightMetric : 1.8 kg
  • FilterTechnology : Cromatografia a scambio anionico
  • Diametro complessivo (misure metriche) : 24.1 cm

Dettagli del prodotto

The Q-functional nonwoven provides reduction of turbidity (when present) and DNA. It also provides a portion of the product’s AEX capacity for HCP and virus reduction. Guanidinium functionalised membrane downstream of the functionalised nonwoven provides additional AEX polishing capacity. The novel guanidinium functionality of the downstream AEX polishing membrane mimics the amino acid, arginine, one of the three positively charged naturally occurring standard amino acids that make up proteins and is responsible for viral clearance and high salt tolerance.
  • Unaffected by process fluid turbidity up to 40 NTU.
  • The 3M™ Polisher ST is a single use multi-mechanism membrane adsorber which contains a Q-functional anion exchange non woven media and guanidinium functionalised membrane. This product removes residual turbidity, DNA and HCP and provides robust virus clearance for improved downstream/polishing purification.
  • Single-use technology as a cost-efficient option to increase biomass production by delivering high purity and yield in the downstream polishing unit operation in therapeutic recombinant protein process in biologically relevant operating conditions.
  • Replaces downstream AEX polishing column for reduction of HCP and virus in a salt tolerant (ST) manner as a single-use solution.
  • Provides DNA reduction in a salt tolerant (ST) manner compared with conventional Q-functional AEX resins.

Specifiche del prodotto

MicronRating
MicronRating

0.8 μm

Fine modifica
Fine modifica

3/4 in Sanitary Connectors

Portata (misure metriche)
Portata (misure metriche)

1020 ml/min

Settori
Settori

Produzione biofarmaceutica

Applicazioni
Applicazioni

Scambio anionico

Nome categoria
Nome categoria

Filtri cromatografici

Serie prodotto
Serie prodotto

Lucidatrice ST

OverallDiameterImperial
OverallDiameterImperial

9.49 in

Portata (misure imperiali)
Portata (misure imperiali)

0.224 gal/min

Tipo di filtro
Tipo di filtro

Monouso

OverallHeightImperial
OverallHeightImperial

5.98 in

Altezza complessiva (misure metriche)
Altezza complessiva (misure metriche)

15.2 cm

NetWeightMetric
NetWeightMetric

1.8 kg

FilterTechnology
FilterTechnology

Cromatografia a scambio anionico

Diametro complessivo (misure metriche)
Diametro complessivo (misure metriche)

24.1 cm

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