3M™ Emphaze™ AEX Hybrid Purifier

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About the product

3M™ Emphaze AEX Hybrid Purifier is our single-use sterilisable and sanitisable. The all-synthetic purification media that contains a Q-functional anion exchange media and a fine particle and bioburden reduction membrane.

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Product name	Product ID	Overall Diameter (Imperial)	Overall Diameter (Metric)	Overall Height (Imperial)	Overall Height (Metric)	End Modification	Micron Rating	FlowRateImperial	Flow Rate (Metric)	FilterType	NetWeightMetric	Application	Filter Technology	Industries	Product Series	Brand	Category name
3M™ Emphaze™ AEX Series Hybrid Purifier BV120R, EMP513AEX020R, 1/Case	Product ID 7100166976	Overall Diameter (Imperial) 8.5 in	Overall Diameter (Metric) 21.6 cm	Overall Height (Imperial) 4.06 in	Overall Height (Metric) 10.3 cm	End Modification 3/4 in Sanitary Connectors	Micron Rating 0.2 μm	FlowRateImperial 0.022 gal/min	Flow Rate (Metric) 100 ml/min	FilterType Single Use	NetWeightMetric 1.1 kg	Application Harvest And Clarification	Filter Technology Anion exchange chromatography	Industries Biopharmaceutical manufacturing	Product Series Emphaze AEX	Brand Emphaze™	Category name Chromatography Filters
3M™ Emphaze™ AEX Series Hybrid Purifier BV8, EMP303AEX020R, Sanitary,2/Case	Product ID 7100158434	Overall Diameter (Imperial) 3.03 in	Overall Diameter (Metric) 7.7 cm	Overall Height (Imperial) 3.46 in	Overall Height (Metric) 8.8 cm	End Modification 3/4 in Sanitary Connectors	Micron Rating 0.2 μm	FlowRateImperial 0.002 gal/min	Flow Rate (Metric) 8 ml/min	FilterType Single Use	NetWeightMetric 77 g	Application Harvest And Clarification	Filter Technology Anion exchange chromatography	Industries Biopharmaceutical manufacturing	Product Series Emphaze AEX	Brand Emphaze™	Category name Chromatography Filters
3M™ Emphaze™ AEX Series Hybrid Purifier BV8R, EMP301AEX020R, Luer,2/Case	Product ID 7100158433	Overall Diameter (Imperial) 3.03 in	Overall Diameter (Metric) 7.7 cm	Overall Height (Imperial) 1.77 in	Overall Height (Metric) 4.5 cm	End Modification Luer Lock	Micron Rating 0.2 μm	FlowRateImperial 0.002 gal/min	Flow Rate (Metric) 8 ml/min	FilterType Single Use	NetWeightMetric 71 g	Application Harvest And Clarification	Filter Technology Anion exchange chromatography	Industries Biopharmaceutical manufacturing	Product Series Emphaze AEX	Brand Emphaze™	Category name Chromatography Filters

Product details

Remove impurities in biopharmaceutical process streams such as DNA, host cell proteins (HCP) and viruses with our all-synthetic, single use 3M™ Emphaze AEX Hybrid Purifier. The composite purification media is comprised of three primary components: anion exchange nonwoven, microporous membrane, and membrane support. The anion exchange media is composed of four layers of polypropylene nonwoven with a covalently attached quaternary ammonium functional polymer. The bioburden reduction membrane is a highly asymmetric polyamide membrane which has nine zones of decreasing pore size, spanning approximately a 20 X range, and terminating with a 0.2 μm rated qualifying layer. This is followed by a polypropylene nonwoven used as a support layer in the capsule. Capsules There are two primary capsule configurations for the Emphaze AEX Hybrid Purifier, Laboratory and Scale-up capsules: - The Laboratory capsule (BV8) has an 8ml bed volume - The Scale-up capsules are constructed from a lenticular media cell design having bed volumes of 120 mls and 360 mls (BV 120 and BV 360 respectively) - The Production capsules are scaled to meet your manufacturing requirements and utilise manifolds in a holder for ease of use A full support package is available for 3M Emphaze AEX Hybrid Purifiers. This package includes Installation and Operation Guides, a Certificate of Quality and a Regulatory Support File.

All-synthetic, highly functionalised media (contains no naturally-derived materials)
Asymmetric membrane ending with a 0.2 µm bioburden reduction zone
Excellent mAb recovery, often equal to or greater than 95%
Substantial turbidity, DNA, HCP and bioburden reduction
Reduced surface area requirement of the downstream sterilising grade membrane
May offer differentiated protection to the protein A column for enhanced contaminant clearance performance
All product components comply with United States Pharmacopeia (USP) <88> Class VI 70°C Biological Reactivity Tests, in vivo
Autoclavable

Suggested Applications

Use for the clarification of mammalian cell cultures and to optimise downstream processes for monoclonal antibodies (mAbs)

Product specifications

FlowRateMetric	FlowRateMetric 100 ml/min, 8 ml/min
Industries	Industries Biopharmaceutical manufacturing
MicronRating	MicronRating 0.2 μm
OverallDiameterMetric	OverallDiameterMetric 7.7 cm
Net Weight (Metric)	Net Weight (Metric) 71 g, 77 g
Filter Technology	Filter Technology Anion exchange chromatography
Micron Rating	Micron Rating 0.2 μm
Product Series	Product Series Emphaze AEX
Flow Rate (Metric)	Flow Rate (Metric) 8 ml/min
EndModification	EndModification Luer Lock, 3/4 in Sanitary Connectors
categoryName	categoryName Chromatography Filters
Flow Rate (Imperial)	Flow Rate (Imperial) 0.022 gal/min, 0.002 gal/min
Brand	Brand Emphaze™
Overall Height (Imperial)	Overall Height (Imperial) 4.06 in, 1.77 in, 3.46 in
Overall Diameter (Imperial)	Overall Diameter (Imperial) 8.5 in, 3.03 in
OverallHeightMetric	OverallHeightMetric 4.5 cm
NetWeightMetric	NetWeightMetric 1.1 kg
Overall Diameter (Metric)	Overall Diameter (Metric) 21.6 cm, 7.7 cm
End Modification	End Modification 3/4 in Sanitary Connectors
Filter Type	Filter Type Single Use
Category name	Category name Chromatography Filters
FilterTechnology	FilterTechnology Anion exchange chromatography
Application	Application Harvest And Clarification
Overall Height (Metric)	Overall Height (Metric) 10.3 cm, 8.8 cm

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3M™ Emphaze™ AEX Hybrid Purifier

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