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3M™ Emphaze™ AEX Series Hybrid Purifier BV360, EMP533AEX020R, 1/CS

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3M™ Emphaze™ AEX Series Hybrid Purifier BV360, EMP533AEX020R, 1/CS

Om produkten

3M™ Emphaze AEX Hybrid Purifier is our single-use sterilisable and sanitisable. The all-synthetic purification media that contains a Q-functional anion exchange media and a fine particle and bioburden reduction membrane.

Detaljer

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  • Industries : Läkemedelstillverkning
  • Mikrometerklassning : 0.2 μm
  • Filterteknik : Anjonbyteskromatografi
  • Total diameter (metrisk) : 21.6 cm
  • Totalhöjd (imperial) : 5.98 in
  • EndModification : 3/4 in Sanitary Connectors
  • Flödestakt (metrisk) : 300 ml/min
  • Kategorinamn : Kromatografifilter
  • Global Catalog Number : EMP533AEX020R
  • Flödestakt (imperial) : 0.066 gal/min
  • OverallHeightMetric : 15.2 cm
  • Märke : Emphaze™
  • Övergripande Diameter (Imperial) : 8.5 in
  • Filtertyp : Engångsbruk
  • ProductSeries : Emphaze AEX
  • Nettovikt : 1.6 kg
  • Application : Tagning och klargöring

Produktdetaljer

Remove impurities in biopharmaceutical process streams such as DNA, host cell proteins (HCP) and viruses with our all-synthetic, single use 3M™ Emphaze AEX Hybrid Purifier. The composite purification media is comprised of three primary components: anion exchange nonwoven, microporous membrane, and membrane support. The anion exchange media is composed of four layers of polypropylene nonwoven with a covalently attached quaternary ammonium functional polymer. The bioburden reduction membrane is a highly asymmetric polyamide membrane which has nine zones of decreasing pore size, spanning approximately a 20 X range, and terminating with a 0.2 μm rated qualifying layer. This is followed by a polypropylene nonwoven used as a support layer in the capsule. Capsules There are two primary capsule configurations for the Emphaze AEX Hybrid Purifier, Laboratory and Scale-up capsules: - The Laboratory capsule (BV8) has an 8ml bed volume - The Scale-up capsules are constructed from a lenticular media cell design having bed volumes of 120 mls and 360 mls (BV 120 and BV 360 respectively) - The Production capsules are scaled to meet your manufacturing requirements and utilise manifolds in a holder for ease of use A full support package is available for 3M Emphaze AEX Hybrid Purifiers. This package includes Installation and Operation Guides, a Certificate of Quality and a Regulatory Support File.
  • All-synthetic, highly functionalised media (contains no naturally-derived materials)
  • Asymmetric membrane ending with a 0.2 µm bioburden reduction zone
  • Excellent mAb recovery, often equal to or greater than 95%
  • Substantial turbidity, DNA, HCP and bioburden reduction
  • Reduced surface area requirement of the downstream sterilising grade membrane
  • May offer differentiated protection to the protein A column for enhanced contaminant clearance performance
  • All product components comply with United States Pharmacopeia (USP) <88> Class VI 70°C Biological Reactivity Tests, in vivo
  • Autoclavable

Föreslagna användningsområden

  • Use for the clarification of mammalian cell cultures and to optimise downstream processes for monoclonal antibodies (mAbs)

Produktspecifikationer

Industries
Industries

Läkemedelstillverkning

Mikrometerklassning
Mikrometerklassning

0.2 μm

Filterteknik
Filterteknik

Anjonbyteskromatografi

Total diameter (metrisk)
Total diameter (metrisk)

21.6 cm

Totalhöjd (imperial)
Totalhöjd (imperial)

5.98 in

EndModification
EndModification

3/4 in Sanitary Connectors

Flödestakt (metrisk)
Flödestakt (metrisk)

300 ml/min

Kategorinamn
Kategorinamn

Kromatografifilter

Global Catalog Number
Global Catalog Number

EMP533AEX020R

Flödestakt (imperial)
Flödestakt (imperial)

0.066 gal/min

OverallHeightMetric
OverallHeightMetric

15.2 cm

Märke
Märke

Emphaze™

Övergripande Diameter (Imperial)
Övergripande Diameter (Imperial)

8.5 in

Filtertyp
Filtertyp

Engångsbruk

ProductSeries
ProductSeries

Emphaze AEX

Nettovikt
Nettovikt

1.6 kg

Application
Application

Tagning och klargöring

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