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  1. 3M™ Polisher ST

3M™ Polisher ST, BC1020, 1/Case

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3M™ Polisher ST, BC1020, 1/Case

Over het product

The 3M™ Polisher ST is a fully encapsulated single-use anion exchange (AEX) product. It is intended to reduce host cell protein, viruses, and other negatively charged contaminants in a flow-through polishing chromatography mode in biopharmaceutical process streams. The 3M™ Polisher ST is a synthetic, hybrid purifier containing two complementary AEX-functional media: a quaternary ammonium (“Q”) functional nonwoven and a guanidinium-functional membrane.

Details

Bekijk andere productopties
  • Industries : Biofarmaceutische productie
  • Eindaanpassing : 3/4 in Sanitary Connectors
  • Totale hoogte (imperiaal) : 5.98 in
  • Toepassing : Anion exchange
  • Micronage : 0.8 μm
  • OverallDiameterMetric : 24.1 cm
  • Totale hoogte (metrisch) : 15.2 cm
  • OverallDiameterImperial : 9.49 in
  • categoryName : Chromatografiefilters
  • Debiet (metrisch) : 1020 ml/min
  • Debiet : 0.224 gal/min
  • NetWeightMetric : 1.8 kg
  • Productserie : Polisher ST
  • Filtertype : Eenmalig gebruik
  • Filtertechnologie : Anion exchange-chromatografie

Productdetails

The Q-functional nonwoven provides reduction of turbidity (when present) and DNA. It also provides a portion of the product’s AEX capacity for HCP and virus reduction. Guanidinium functionalised membrane downstream of the functionalised nonwoven provides additional AEX polishing capacity. The novel guanidinium functionality of the downstream AEX polishing membrane mimics the amino acid, arginine, one of the three positively charged naturally occurring standard amino acids that make up proteins and is responsible for viral clearance and high salt tolerance.
  • Unaffected by process fluid turbidity up to 40 NTU.
  • The 3M™ Polisher ST is a single use multi-mechanism membrane adsorber which contains a Q-functional anion exchange non woven media and guanidinium functionalised membrane. This product removes residual turbidity, DNA and HCP and provides robust virus clearance for improved downstream/polishing purification.
  • Single-use technology as a cost-efficient option to increase biomass production by delivering high purity and yield in the downstream polishing unit operation in therapeutic recombinant protein process in biologically relevant operating conditions.
  • Replaces downstream AEX polishing column for reduction of HCP and virus in a salt tolerant (ST) manner as a single-use solution.
  • Provides DNA reduction in a salt tolerant (ST) manner compared with conventional Q-functional AEX resins.

Productspecificaties

Industries
Industries

Biofarmaceutische productie

Eindaanpassing
Eindaanpassing

3/4 in Sanitary Connectors

Totale hoogte (imperiaal)
Totale hoogte (imperiaal)

5.98 in

Toepassing
Toepassing

Anion exchange

Micronage
Micronage

0.8 μm

OverallDiameterMetric
OverallDiameterMetric

24.1 cm

Totale hoogte (metrisch)
Totale hoogte (metrisch)

15.2 cm

OverallDiameterImperial
OverallDiameterImperial

9.49 in

categoryName
categoryName

Chromatografiefilters

Debiet (metrisch)
Debiet (metrisch)

1020 ml/min

Debiet
Debiet

0.224 gal/min

NetWeightMetric
NetWeightMetric

1.8 kg

Productserie
Productserie

Polisher ST

Filtertype
Filtertype

Eenmalig gebruik

Filtertechnologie
Filtertechnologie

Anion exchange-chromatografie

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