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3M™ Emphaze™ AEX Series Hybrid Purifier BV5600R, EMP770AEX020R, 16 in,1/Case

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3M™ Emphaze™ AEX Series Hybrid Purifier BV5600R, EMP770AEX020R, 16 in,1/Case
3M™ Emphaze™ AEX Hybrid Purifier Family

Over het product

3M™ Emphaze AEX Hybrid Purifier is our single-use sterilisable and sanitisable. The all-synthetic purification media that contains a Q-functional anion exchange media and a fine particle and bioburden reduction membrane.

  • Categorienaam : Chromatografiefilters
  • Micronage : 0.2 μm
  • OverallDiameterMetric : 45.2 cm
  • Totale hoogte (metrisch) : 20.3 cm
  • OverallDiameterImperial : 17.8 in
  • EndModification : 1 1/2 in Sanitary Connectors
  • Debiet (metrisch) : 4700 ml/min
  • OverallHeightImperial : 7.99 in
  • Debiet : 1.034 gal/min
  • Sectoren : Biofarmaceutische productie
  • FilterType : Eenmalig gebruik
  • Merk : Emphaze™
  • NetWeightMetric : 9.5 kg
  • Productserie : Emphaze AEX
  • FilterTechnology : Anion exchange-chromatografie
  • Application : Oogsten en klaring

Productdetails

Remove impurities in biopharmaceutical process streams such as DNA, host cell proteins (HCP) and viruses with our all-synthetic, single use 3M™ Emphaze AEX Hybrid Purifier. The composite purification media is comprised of three primary components: anion exchange nonwoven, microporous membrane, and membrane support. The anion exchange media is composed of four layers of polypropylene nonwoven with a covalently attached quaternary ammonium functional polymer. The bioburden reduction membrane is a highly asymmetric polyamide membrane which has nine zones of decreasing pore size, spanning approximately a 20 X range, and terminating with a 0.2 μm rated qualifying layer. This is followed by a polypropylene nonwoven used as a support layer in the capsule. Capsules There are two primary capsule configurations for the Emphaze AEX Hybrid Purifier, Laboratory and Scale-up capsules: - The Laboratory capsule (BV8) has an 8ml bed volume - The Scale-up capsules are constructed from a lenticular media cell design having bed volumes of 120 mls and 360 mls (BV 120 and BV 360 respectively) - The Production capsules are scaled to meet your manufacturing requirements and utilise manifolds in a holder for ease of use A full support package is available for 3M Emphaze AEX Hybrid Purifiers. This package includes Installation and Operation Guides, a Certificate of Quality and a Regulatory Support File.
  • All-synthetic, highly functionalised media (contains no naturally-derived materials)
  • Asymmetric membrane ending with a 0.2 µm bioburden reduction zone
  • Excellent mAb recovery, often equal to or greater than 95%
  • Substantial turbidity, DNA, HCP and bioburden reduction
  • Reduced surface area requirement of the downstream sterilising grade membrane
  • May offer differentiated protection to the protein A column for enhanced contaminant clearance performance
  • All product components comply with United States Pharmacopeia (USP) <88> Class VI 70°C Biological Reactivity Tests, in vivo
  • Autoclavable

Voorgestelde toepassingen

  • Use for the clarification of mammalian cell cultures and to optimise downstream processes for monoclonal antibodies (mAbs)

Productspecificaties

Categorienaam
Categorienaam

Chromatografiefilters

Micronage
Micronage

0.2 μm

OverallDiameterMetric
OverallDiameterMetric

45.2 cm

Totale hoogte (metrisch)
Totale hoogte (metrisch)

20.3 cm

OverallDiameterImperial
OverallDiameterImperial

17.8 in

EndModification
EndModification

1 1/2 in Sanitary Connectors

Debiet (metrisch)
Debiet (metrisch)

4700 ml/min

OverallHeightImperial
OverallHeightImperial

7.99 in

Debiet
Debiet

1.034 gal/min

Sectoren
Sectoren

Biofarmaceutische productie

FilterType
FilterType

Eenmalig gebruik

Merk
Merk

Emphaze™

NetWeightMetric
NetWeightMetric

9.5 kg

Productserie
Productserie

Emphaze AEX

FilterTechnology
FilterTechnology

Anion exchange-chromatografie

Application
Application

Oogsten en klaring

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