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Emphaze™ AEX Series Hybrid Purifier BV60, EMP503AEX020R, 1/Case

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Emphaze™ AEX Series Hybrid Purifier BV60, EMP503AEX020R, 1/Case

Over het product

3M™ Emphaze AEX Hybrid Purifier is our single-use sterilisable and sanitisable. The all-synthetic purification media that contains a Q-functional anion exchange media and a fine particle and bioburden reduction membrane.

Details

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  • FlowRateMetric : 50 ml/min
  • Industries : Biofarmaceutische productie
  • MicronRating : 0.2 μm
  • OverallDiameterMetric : 21.6 cm
  • OverallDiameterImperial : 8.5 in
  • EndModification : 3/4 in Sanitary Connectors
  • categoryName : Chromatografiefilters
  • OverallHeightImperial : 4.06 in
  • Global Catalog Number : EMP503AEX020R
  • Debiet : 0.011 gal/min
  • FilterType : Eenmalig gebruik
  • OverallHeightMetric : 10.3 cm
  • NetWeightMetric : 1 kg
  • ProductSeries : Emphaze AEX
  • Trademark2 : Emphaze™
  • FilterTechnology : Anion exchange-chromatografie
  • Application : Oogsten en klaring

Productdetails

Remove impurities in biopharmaceutical process streams such as DNA, host cell proteins (HCP) and viruses with our all-synthetic, single use 3M™ Emphaze AEX Hybrid Purifier. The composite purification media is comprised of three primary components: anion exchange nonwoven, microporous membrane, and membrane support. The anion exchange media is composed of four layers of polypropylene nonwoven with a covalently attached quaternary ammonium functional polymer. The bioburden reduction membrane is a highly asymmetric polyamide membrane which has nine zones of decreasing pore size, spanning approximately a 20 X range, and terminating with a 0.2 μm rated qualifying layer. This is followed by a polypropylene nonwoven used as a support layer in the capsule. Capsules There are two primary capsule configurations for the Emphaze AEX Hybrid Purifier, Laboratory and Scale-up capsules: - The Laboratory capsule (BV8) has an 8ml bed volume - The Scale-up capsules are constructed from a lenticular media cell design having bed volumes of 120 mls and 360 mls (BV 120 and BV 360 respectively) - The Production capsules are scaled to meet your manufacturing requirements and utilise manifolds in a holder for ease of use A full support package is available for 3M Emphaze AEX Hybrid Purifiers. This package includes Installation and Operation Guides, a Certificate of Quality and a Regulatory Support File.
  • All-synthetic, highly functionalised media (contains no naturally-derived materials)
  • Asymmetric membrane ending with a 0.2 µm bioburden reduction zone
  • Excellent mAb recovery, often equal to or greater than 95%
  • Substantial turbidity, DNA, HCP and bioburden reduction
  • Reduced surface area requirement of the downstream sterilising grade membrane
  • May offer differentiated protection to the protein A column for enhanced contaminant clearance performance
  • All product components comply with United States Pharmacopeia (USP) <88> Class VI 70°C Biological Reactivity Tests, in vivo
  • Autoclavable

Voorgestelde toepassingen

  • Use for the clarification of mammalian cell cultures and to optimise downstream processes for monoclonal antibodies (mAbs)

Productspecificaties

FlowRateMetric
FlowRateMetric

50 ml/min

Industries
Industries

Biofarmaceutische productie

MicronRating
MicronRating

0.2 μm

OverallDiameterMetric
OverallDiameterMetric

21.6 cm

OverallDiameterImperial
OverallDiameterImperial

8.5 in

EndModification
EndModification

3/4 in Sanitary Connectors

categoryName
categoryName

Chromatografiefilters

OverallHeightImperial
OverallHeightImperial

4.06 in

Global Catalog Number
Global Catalog Number

EMP503AEX020R

Debiet
Debiet

0.011 gal/min

FilterType
FilterType

Eenmalig gebruik

OverallHeightMetric
OverallHeightMetric

10.3 cm

NetWeightMetric
NetWeightMetric

1 kg

ProductSeries
ProductSeries

Emphaze AEX

Trademark2
Trademark2

Emphaze™

FilterTechnology
FilterTechnology

Anion exchange-chromatografie

Application
Application

Oogsten en klaring

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