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  1. 3M™ Polisher ST

3M™ Polisher ST, BC25, Sanitary, 2/Case

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3M™ Polisher ST, BC25, Sanitary, 2/Case
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Om produktet

The 3M™ Polisher ST is a fully encapsulated single-use anion exchange (AEX) product. It is intended to reduce host cell protein, viruses, and other negatively charged contaminants in a flow-through polishing chromatography mode in biopharmaceutical process streams. The 3M™ Polisher ST is a synthetic, hybrid purifier containing two complementary AEX-functional media: a quaternary ammonium (“Q”) functional nonwoven and a guanidinium-functional membrane.

Detaljer

Vis øvrige produktmuligheder
  • MicronRating : 0.8 μm
  • Afslut ændring : 3/4 in Sanitary Connectors
  • Samlet højde (metrisk standard) : 8.6 cm
  • Flowhastighed (britisk mål) : 0.005 gal/min
  • Total Diameter (Imperial) : 3.03 in
  • Flowhastighed (metrisk) : 25 ml/min
  • Samlet diameter (metrisk standard) : 7.7 cm
  • Filterteknologi : Anion-udvekslingskromatografi
  • OverallHeightImperial : 3.39 in
  • NetWeightMetric : 78 g
  • Brancher : Biofarmaceutisk produktion
  • Kategorinavn : Kromatografifiltre
  • Filtertype : Engangsbrug
  • Produktserie : Polisher ST
  • Applikation : Anionudveksling

Produktdetaljer

The Q-functional nonwoven provides reduction of turbidity (when present) and DNA. It also provides a portion of the product’s AEX capacity for HCP and virus reduction. Guanidinium functionalised membrane downstream of the functionalised nonwoven provides additional AEX polishing capacity. The novel guanidinium functionality of the downstream AEX polishing membrane mimics the amino acid, arginine, one of the three positively charged naturally occurring standard amino acids that make up proteins and is responsible for viral clearance and high salt tolerance.
  • Unaffected by process fluid turbidity up to 40 NTU.
  • The 3M™ Polisher ST is a single use multi-mechanism membrane adsorber which contains a Q-functional anion exchange non woven media and guanidinium functionalised membrane. This product removes residual turbidity, DNA and HCP and provides robust virus clearance for improved downstream/polishing purification.
  • Single-use technology as a cost-efficient option to increase biomass production by delivering high purity and yield in the downstream polishing unit operation in therapeutic recombinant protein process in biologically relevant operating conditions.
  • Replaces downstream AEX polishing column for reduction of HCP and virus in a salt tolerant (ST) manner as a single-use solution.
  • Provides DNA reduction in a salt tolerant (ST) manner compared with conventional Q-functional AEX resins.

Produktspecifikationer

MicronRating
MicronRating

0.8 μm

Afslut ændring
Afslut ændring

3/4 in Sanitary Connectors

Samlet højde (metrisk standard)
Samlet højde (metrisk standard)

8.6 cm

Flowhastighed (britisk mål)
Flowhastighed (britisk mål)

0.005 gal/min

Total Diameter (Imperial)
Total Diameter (Imperial)

3.03 in

Flowhastighed (metrisk)
Flowhastighed (metrisk)

25 ml/min

Samlet diameter (metrisk standard)
Samlet diameter (metrisk standard)

7.7 cm

Filterteknologi
Filterteknologi

Anion-udvekslingskromatografi

OverallHeightImperial
OverallHeightImperial

3.39 in

NetWeightMetric
NetWeightMetric

78 g

Brancher
Brancher

Biofarmaceutisk produktion

Kategorinavn
Kategorinavn

Kromatografifiltre

Filtertype
Filtertype

Engangsbrug

Produktserie
Produktserie

Polisher ST

Applikation
Applikation

Anionudveksling