3M™ Polisher ST
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About the product
The 3M™ Polisher ST is a fully encapsulated single-use anion exchange (AEX) product. It is intended to reduce host cell protein, viruses, and other negatively charged contaminants in a flow-through polishing chromatography mode in biopharmaceutical process streams. The 3M™ Polisher ST is a synthetic, hybrid purifier containing two complementary AEX-functional media: a quaternary ammonium (“Q”) functional nonwoven and a guanidinium-functional membrane.
Product details
- Unaffected by process fluid turbidity up to 40 NTU.
- The 3M™ Polisher ST is a single use multi-mechanism membrane adsorber which contains a Q-functional anion exchange non woven media and guanidinium functionalised membrane. This product removes residual turbidity, DNA and HCP and provides robust virus clearance for improved downstream/polishing purification.
- Single-use technology as a cost-efficient option to increase biomass production by delivering high purity and yield in the downstream polishing unit operation in therapeutic recombinant protein process in biologically relevant operating conditions.
- Replaces downstream AEX polishing column for reduction of HCP and virus in a salt tolerant (ST) manner as a single-use solution.
- Provides DNA reduction in a salt tolerant (ST) manner compared with conventional Q-functional AEX resins.
Product specifications
| Industries |
Industries
Biopharmaceutical manufacturing |
| Net Weight (Metric) |
Net Weight (Metric)
10 g, 72 g, 1.1 kg |
| Filter Technology |
Filter Technology
Anion exchange chromatography |
| Micron Rating |
Micron Rating
0.8 μm |
| OverallDiameterImperial |
OverallDiameterImperial
1.69 in |
| categoryName |
categoryName
Chromatography Filters |
| Flow Rate (Imperial) |
Flow Rate (Imperial)
0.001 gal/min |
| OverallHeightImperial |
OverallHeightImperial
1.89 in, 1.77 in, 2.32 in, 3.98 in |
| OverallHeightMetric |
OverallHeightMetric
4.5 cm |
| FlowRateImperial |
FlowRateImperial
0 gal/min, 0.005 gal/min, 0.037 gal/min |
| NetWeightMetric |
NetWeightMetric
15.5 g |
| End Modification |
End Modification
Luer Lock |
| ProductSeries |
ProductSeries
Polisher ST |
| Category name |
Category name
Chromatography Filters |
| Overall Height (Metric) |
Overall Height (Metric)
4.8 cm, 5.9 cm, 10.1 cm |
| FlowRateMetric |
FlowRateMetric
25 ml/min, 4 ml/min |
| MicronRating |
MicronRating
0.8 μm |
| OverallDiameterMetric |
OverallDiameterMetric
4.3 cm |
| Flow Rate (Metric) |
Flow Rate (Metric)
1 ml/min, 170 ml/min |
| EndModification |
EndModification
3/4 in Sanitary Connectors |
| FilterType |
FilterType
Single Use |
| Overall Diameter (Imperial) |
Overall Diameter (Imperial)
3.03 in, 9.49 in |
| Overall Diameter (Metric) |
Overall Diameter (Metric)
7.7 cm, 4.3 cm, 24.1 cm |
| Filter Type |
Filter Type
Single Use |
| FilterTechnology |
FilterTechnology
Anion exchange chromatography |
| Application |
Application
Anion exchange |
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